Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 2/20 | 0.35 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | NNMT | P40261 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38665739 | 0.85 | PLAU (0.36) | PLAUSIRT6CYP1A2NNMTLMNA | |
| SCHEMBL38663555 | 0.80 | NPC1 (0.33) | MEN1NPC1RAB9AKMT2ATP53 | |
| SCHEMBL30103427 | 0.74 | PLAU (0.43) | PLAUSIRT6CYP1A2NNMTHPGDS | |
| SCHEMBL18940888 | 0.71 | COMT (0.35) | CYP1A2MAPTLMNAALDH1A1CYP3A4 | |
| SCHEMBL23629315 | 0.70 | HSD17B10 (0.41) | MEN1NPC1RAB9AKMT2AMAPT | |
| SCHEMBL38662970 | 0.70 | NPSR1 (0.41) | MEN1NPC1RAB9AKMT2ATP53 | |
| SCHEMBL38662973 | 0.70 | NAMPT (0.34) | PLAUMEN1NPC1RAB9AKMT2A | |
| SCHEMBL18940882 | 0.68 | CHRM2 (0.37) | MEN1NPC1KMT2ACYP1A2TP53 | |
| SCHEMBL24912642 | 0.67 | TDP1 (0.38) | PLAUMEN1KMT2ACYP1A2MAPT | |
| SCHEMBL18940878 | 0.66 | COMT (0.49) | NPC1RAB9ACYP1A2MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026107422-A1 | 6-(PYRIDIN-4-YL)-1H-BENZO[D]IMIDAZOLE DERIVATIVES AS CAMK2 INHIBITORS FOR THE TREATMENT OF HEART FAILURE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2026-05-21 | — | — | WO | disclosed |