SCHEMBL38664809

SCHEMBL38664809

CC(=O)Oc1ccc(C=Cc2ccc3c(c2)C(C(=O)Oc2c(C)cccc2C)c2ccccc2N3C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
MAPT P10636 2/20 0.41
TTR P02766 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
TUBB4A P04350 3/20 0.39
TUBB P07437 3/20 0.39
TUBA3C P0DPH7 3/20 0.39
TUBA1B P68363 3/20 0.39
TUBA4A P68366 3/20 0.39
TUBB4B P68371 3/20 0.39
TUBB3 Q13509 3/20 0.39
TUBB2A Q13885 3/20 0.39
TUBB8 Q3ZCM7 3/20 0.39
TUBA3E Q6PEY2 3/20 0.39
TUBA1A Q71U36 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38662446 0.89 HDAC4 (0.40) KMT2AMEN1MAPTTTRSMN1; SMN2
SCHEMBL38663301 0.81 HDAC4 (0.41) KMT2AMEN1MAPTSMN1; SMN2LMNA
SCHEMBL38664478 0.81 HDAC4 (0.51) KMT2AMEN1MAPTSMN1; SMN2KDM4E
SCHEMBL6254107 0.81 HDAC4 (0.51) KMT2AMEN1MAPTSMN1; SMN2KDM4E
SCHEMBL4197113 0.80 TTR (0.40) KMT2AMEN1MAPTTTRSMN1; SMN2
SCHEMBL38661832 0.78 HDAC4 (0.45) KMT2AMEN1MAPTSMN1; SMN2LMNA
SCHEMBL4187769 0.77 TTR (0.43) KMT2AMAPTTTRSMN1; SMN2TP53
SCHEMBL38664719 0.77 ATM (0.40) KMT2AMAPTSMN1; SMN2KDM4ELMNA
SCHEMBL13061976 0.76 HDAC4 (0.49) KMT2AMEN1MAPTTTRSMN1; SMN2
SCHEMBL14564645 0.75 HDAC4 (0.43) KMT2AMEN1MAPTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099510-A1 RESILIENT MARKER COMPOUNDS MINTON, TREHARNE & DAVIES LIMITED (GB) 2026-05-15 WO disclosed