SCHEMBL38666359

SCHEMBL38666359

COc1ccc(CC(NC(=O)OCC2c3ccccc3-c3ccccc32)C(=O)O)c(OC)c1

nearest known ligand 0.55

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 5/20 0.53
MDM4 O15151 3/20 0.51
TP53 P04637 3/20 0.51
ALDH1A1 P00352 1/20 0.47
ALOX15 P16050 1/20 0.47
CASP3 P42574 1/20 0.46
SLC17A5 Q9NRA2 1/20 0.46
TAS1R3 Q7RTX0 1/20 0.45
TAS1R1 Q7RTX1 1/20 0.45
TLR2 O60603 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31168844 0.92 MDM2 (0.46) MDM2MDM4TP53ALDH1A1ALOX15
SCHEMBL22444667 0.89 MDM2 (0.53) MDM2MDM4TP53CASP3SLC17A5
SCHEMBL29557307 0.89 MDM4 (0.52) MDM2MDM4TP53ALDH1A1CASP3
SCHEMBL22444637 0.89 MDM4 (0.52) MDM2MDM4TP53ALDH1A1CASP3
SCHEMBL17054258 0.89 MDM4 (0.52) MDM2MDM4TP53ALDH1A1CASP3
SCHEMBL29855217 0.89 MDM4 (0.52) MDM2MDM4TP53ALDH1A1CASP3
SCHEMBL25259836 0.87 MDM2 (0.53) MDM2MDM4TP53CASP3SLC17A5
SCHEMBL25259834 0.87 MDM2 (0.53) MDM2MDM4TP53CASP3SLC17A5
SCHEMBL13928511 0.87 MDM2 (0.47) MDM2MDM4TP53ALDH1A1ALOX15
SCHEMBL233300 0.87 MDM2 (0.47) MDM2MDM4TP53ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026107423-A1 ORAL PEPTIDES AND USES THEREOF FOR WEIGHT LOSS, WEIGHT MAINTENANCE, AND MANAGEMENT OF METABOLIC CONDITIONS METSERA, INC. (US) 2026-05-21 WO disclosed