Known targets — ChEMBL curated mechanism
SLC6A2SLC6A3SSTR1SSTR2SSTR3SSTR5
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL10799232 | 0.97 | SLC22A6 (0.39) | TDP1SLC22A6GABRR1CA4LMNA | |
| Aspartic Acid SCHEMBL120391 | 0.97 | SLC22A6 (0.39) | TDP1SLC22A6GABRR1CA4LMNA | |
| Aspartic Acid SCHEMBL28275864 | 0.95 | SLC22A6 (0.38) | TDP1SLC22A6GABRR1CA4LMNA | |
| Aspartic Acid SCHEMBL4195248 | 0.95 | TDP1 (0.42) | TDP1SLC22A6GABRR1CA4LMNA | |
| Aspartic Acid SCHEMBL317389 | 0.95 | SLC22A6 (0.38) | TDP1SLC22A6GABRR1CA4LMNA | |
| Aspartic Acid SCHEMBL20454596 | 0.95 | SLC22A6 (0.38) | TDP1SLC22A6GABRR1CA4LMNA | |
| Aspartic Acid SCHEMBL4197042 | 0.95 | TDP1 (0.42) | TDP1SLC22A6GABRR1CA4LMNA | |
| Aspartic Acid SCHEMBL1987594 | 0.95 | SLC22A6 (0.41) | TDP1SLC22A6GABRR1CA4LMNA | |
| Aspartic Acid SCHEMBL3859423 | 0.93 | GRIK1 (0.43) | TDP1GRIK1GRIK2GRM1GRM2 | |
| Aspartic Acid SCHEMBL13836481 | 0.93 | SLC22A6 (0.36) | TDP1SLC22A6GABRR1CA4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294672-B2 | Method to form polymeric materials by reverse suspension/emulsion polymerization and compositions formed using that method | POLYMER CHEMISTRY INNOVATIONS, INC. (US) | 2007-11-13 | — | — | US | claimed |
| US-20040192837-A1 | Method to form polymeric materials by reverse suspension/emulsion polymerization and compositions formed using that method | POLYMER CHEMISTRY INNOVATIONS, INC. | 2004-09-30 | — | — | US | claimed |
| US-20190203119-A1 | Amino Acid, Carbohydrate and Acrylamide Polymers useful as Flocculants in Agricultural and Industrial Settings | AQUERO COMPANY, LLC (US) | 2019-07-04 | — | — | US | disclosed |
| US-9994767-B2 | Amino acid, carbohydrate and acrylamide polymers useful as flocculants in agricultural and industrial settings | AQUERO COMPANY, LLC (US) | 2018-06-12 | — | — | US | disclosed |
| EP-1966347-B1 | CARBOHYDRATE AND ACRYLAMIDE POLYMERS USEFUL AS FLOCCULANTS IN PROCESS WATER OBTAINED FROM AN OIL-SANDS MINING OPERATION | AQUERO COMPANY LLC (US) | 2017-05-03 | — | — | EP | disclosed |
| US-7595002-B2 | Use of amino acid and carbohydrate polymers in soil retention, water conservation, and water clarification | AQUERO COMPANY (US) | 2009-09-29 | — | — | US | disclosed |
| US-7595007-B2 | Amino acid and carbohydrate polymers for use in soil retention, water conservation, water clarification, and dust control | AQUERO COMPANY (US) | 2009-09-29 | — | — | US | disclosed |
| US-20090127205-A1 | AMINO ACID, CARBOHYDRATE AND ACRYLAMIDE POLYMERS USEFUL AS FLOCCULANTS IN AGRICULTURAL AND INDUSTRIAL SETTINGS | AQUERO COMPANY, LLC | 2009-05-21 | — | — | US | disclosed |
| EP-1966347-A2 | AMINO ACID, CARBOHYDRATE AND ACRYLAMIDE POLYMERS USEFUL AS FLOCCULANTS IN AGRICULTURAL AND INDUSTRIAL SETTINGS | Aquero Company LLC (US) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007047481-A2 | AMINO ACID, CARBOHYDRATE AND ACRYLAMIDE POLYMERS USEFUL AS FLOCCULANTS IN AGRICULTURAL AND INDUSTRIAL SETTINGS | AQUERO COMPANY, LLC (US) | 2007-04-26 | — | — | WO | disclosed |
| US-20070084800-A1 | Use of amino acid and carbohydrate polymers in soil retention, water conservation, and water clarification | AQUERO COMPANY, LCC | 2007-04-19 | — | — | US | disclosed |
| US-20070085055-A1 | Amino acid and carbohydrate polymers for use in soil retention, water conservation, water clarification, and dust control | AQUERO COMPANY, LCC | 2007-04-19 | — | — | US | disclosed |