Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 2/20 | 0.31 |
| ▸ | UGCG | Q16739 | 2/20 | 0.31 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979409 | 0.85 | KMT2A (0.67) | KMT2AMEN1ITPR1MTNR1AALDH1A1 | |
| SCHEMBL388102 | 0.84 | KMT2A (0.60) | KMT2AMEN1ITPR1MTNR1AALDH1A1 | |
| SCHEMBL3491061 | 0.81 | KMT2A (0.56) | KMT2AMEN1ITPR1MTNR1AALDH1A1 | |
| SCHEMBL3025741 | 0.79 | KMT2A (0.65) | KMT2AMEN1ITPR1MTNR1AALDH1A1 | |
| SCHEMBL6282093 | 0.79 | KMT2A (0.68) | KMT2AMEN1ITPR1MTNR1AALDH1A1 | |
| SCHEMBL16192993 | 0.79 | KMT2A (0.68) | KMT2AMEN1ITPR1MTNR1AALDH1A1 | |
| SCHEMBL2181341 | 0.76 | KMT2A (0.65) | KMT2AMEN1MTNR1AALDH1A1KDM4E | |
| SCHEMBL3408760 | 0.75 | KMT2A (0.63) | KMT2AMEN1ITPR1MTNR1AALDH1A1 | |
| SCHEMBL13485129 | 0.75 | KMT2A (0.63) | KMT2AMEN1ITPR1MTNR1AALDH1A1 | |
| SCHEMBL113945 | 0.75 | KMT2A (1.00) | KMT2AMEN1ITPR1MTNR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0826780-A1 | Detection of nucleic acids using G-quartets | Becton, Dickinson and Company (US) | 1998-03-04 | — | — | EP | claimed |
| US-5691145-A | OLIGONUCLEOTIDE LABELLED WITH DONOR FLUOROPHORE AND ACCEPTOR DYE; DETECTING CHANGE IN FLUORESCENCE | BECTON, DICKINSON AND COMPANY (US) | 1997-11-25 | — | — | US | claimed |
| CN-107868815-B | Method for reducing quantitative errors caused by reaction volume deviations in digital polymerase chain reaction | 豪夫迈·罗氏有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-107868816-B | Method for determining the amount of a nucleic acid of interest in an untreated sample | 豪夫迈·罗氏有限公司 | 2023-07-25 | — | — | CN | disclosed |
| US-20220136074-A1 | ISOTHERMAL AMPLIFICATION AND AMBIENT VISUALIZATION IN A SINGLE TUBE FOR THE DETECTION OF SARS-COV-2 USING LOOP-MEDIATED AMPLIFICATION AND CRISPR TECHNOLOGY | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2022-05-05 | — | — | US | disclosed |
| US-11053541-B2 | Systems and methods for sequencing in emulsion based microfluidics | BIO-RAD LABORATORIES, INC. (US) | 2021-07-06 | — | — | US | disclosed |
| US-10343167-B2 | Integrated microfluidic system, method and kit for performing assays | BIO-RAD LABORATORIES, INC. (US) | 2019-07-09 | — | — | US | disclosed |
| EP-3004391-B1 | METHODS FOR SEQUENCING IN EMULSION BASED MICROFLUIDICS | BIO RAD LABORATORIES (US) | 2019-03-27 | — | — | EP | disclosed |
| US-10012592-B2 | Managing variation in spectroscopic intensity measurements through the use of a reference component | BIO-RAD LABORATORIES, INC. (US) | 2018-07-03 | — | — | US | disclosed |
| US-20180073074-A1 | SYSTEMS AND METHODS FOR SEQUENCING IN EMULSION BASED MICROFLUIDICS | BIO-RAD LABORATORIES, INC. | 2018-03-15 | — | — | US | disclosed |
| US-20180045648-A1 | MANAGING VARIATION IN SPECTROSCOPIC INTENSITY MEASUREMENTS THROUGH THE USE OF A REFERENCE COMPONENT | BIO RAD LABORATORIES (US) | 2018-02-15 | — | — | US | disclosed |
| US-20130344485-A1 | NUCLEIC ACID TARGET DETECTION USING A DETECTOR, A PROBE AND AN INHIBITOR | GNUBIO, INC. (US) | 2013-12-26 | — | — | US | disclosed |
| EP-2649202-A1 | NUCLEIC ACID TARGET DETECTION USING A DETECTOR, A PROBE AND AN INHIBITOR | GnuBIO, Inc. (US) | 2013-10-16 | — | — | EP | disclosed |
| WO-2013122826-A1 | CASCADED ADDITION OF TARGET SPECIFIC UNIVERSAL ADAPTERS TO NUCLEIC ACIDS | GNUBIO, INC. (US) | 2013-08-22 | — | — | WO | disclosed |
| WO-2012078710-A1 | NUCLEIC ACID TARGET DETECTION USING A DETECTOR, A PROBE AND AN INHIBITOR | GNUBIO, INC. (US) | 2012-06-14 | — | — | WO | disclosed |
| EP-1583840-A4 | TARGET-DEPENDENT TRANSCRIPTION | EPICT TECHNOLOGIES (US) | 2009-03-18 | — | — | EP | disclosed |
| EP-1583840-A2 | TARGET-DEPENDENT TRANSCRIPTION | Epicentre Technologies (US) | 2005-10-12 | — | — | EP | disclosed |
| US-6864058-B2 | Vaccinia topoisomerases I-based assays for detection of specific DNA breaks | BAYLOR COLLEGE OF MEDICINE (US) | 2005-03-08 | — | — | US | disclosed |
| WO-2004058989-A2 | TARGET-DEPENDENT TRANSCRIPTION | EPICENTRE TECHNOLOGIES (US) | 2004-07-15 | — | — | WO | disclosed |
| US-20040091859-A1 | Vaccinia topoisomerases I-based assays for detection of specific DNA breaks | BAYLOR | 2004-05-13 | — | — | US | disclosed |