Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 20/20 | 0.61 |
| ▸ | NR1H3 | Q13133 | 20/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3858992 | 0.94 | NR1H2 (0.62) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL3863674 | 0.93 | NR1H2 (0.61) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL1408227 | 0.87 | NR1H2 (0.77) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL3859203 | 0.87 | NR1H2 (0.62) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL3858795 | 0.87 | NR1H2 (0.62) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL3882751 | 0.85 | NR1H2 (0.64) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL1408008 | 0.85 | NR1H2 (0.69) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL1407726 | 0.85 | NR1H2 (0.69) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL1407606 | 0.84 | NR1H2 (0.68) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL1408294 | 0.84 | NR1H2 (0.68) | NR1H2NR1H3NR1I2NR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592363-B2 | Indazoles | WYETH (US) | 2009-09-22 | — | — | US | claimed |