Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.64 |
| ▸ | CA9 | Q16790 | 1/20 | 0.64 |
| ▸ | FKBP4 | Q02790 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23530411 | 1.00 | CA1 (0.64) | CA1CA9FKBP4ALDH1A1LMNA | |
| SCHEMBL2973595 | 1.00 | CA1 (0.64) | CA1CA9FKBP4ALDH1A1LMNA | |
| SCHEMBL1539260 | 1.00 | CA1 (0.64) | CA1CA9FKBP4ALDH1A1LMNA | |
| SCHEMBL2973591 | 1.00 | CA1 (0.64) | CA1CA9FKBP4ALDH1A1LMNA | |
| SCHEMBL2973589 | 1.00 | CA1 (0.64) | CA1CA9FKBP4ALDH1A1LMNA | |
| SCHEMBL1539158 | 0.96 | CA1 (0.58) | CA1CA9FKBP4ALDH1A1LMNA | |
| SCHEMBL29047147 | 0.88 | CA1 (0.62) | CA1CA9FKBP4ALDH1A1LMNA | |
| SCHEMBL3876370 | 0.84 | CA1 (0.41) | CA1CA9FKBP4 | |
| SCHEMBL7053729 | 0.82 | CA1 (0.94) | CA1CA9FKBP4ALDH1A1LMNA | |
| SCHEMBL189541 | 0.82 | CA1 (0.94) | CA1CA9FKBP4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2301927-B1 | Cyclopropanated macrocyclic lactone | INT FLAVORS & FRAGRANCES INC (US) | 2016-01-27 | — | — | EP | disclosed |
| US-20090087402-A1 | Cyclopropanated Macrocyclic Ketones and Lactones | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2009-04-02 | — | — | US | disclosed |
| US-20090081150-A1 | CYCLOPROPANATED MACROCYCLIC KETONES AND LACTONES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2009-03-26 | — | — | US | disclosed |
| EP-1712538-A1 | Cyclopropanated macrocyclic ketones and lactones | INTERNATIONAL FLAVORS & FRAGRANCES, INC. (US) | 2006-10-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090087402-A1 | Cyclopropanated Macrocyclic Ketones and Lactones | CBR3, CBR1, DCXR | CA1 2934/4885CA9 1513/4885FKBP4 814/4885 |
| US-20090081150-A1 | CYCLOPROPANATED MACROCYCLIC KETONES AND LACTONES | CBR3, CBR1, DCXR | CA1 2934/4885CA9 1513/4885FKBP4 814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.