⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10814740 | 0.81 | — | — | |
| SCHEMBL4871784 | 0.70 | — | — | |
| SCHEMBL10338534 | 0.69 | — | — | |
| SCHEMBL10338533 | 0.69 | — | — | |
| SCHEMBL2846075 | 0.65 | — | — | |
| SCHEMBL421978 | 0.65 | — | — | |
| SCHEMBL9492366 | 0.63 | — | — | |
| SCHEMBL7879267 | 0.60 | — | — | |
| SCHEMBL7630454 | 0.58 | — | — | |
| SCHEMBL11700376 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250320175-A1 | Acetoacetate Based Ketals | ARXADA AG (CH) | 2025-10-16 | — | — | US | claimed |
| US-20250002446-A1 | Acetoacetate Based Ketals | ARXADA AG (CH) | 2025-01-02 | — | — | US | claimed |
| EP-4412987-A1 | ACETOACETATE BASED KETALS | Arxada AG (CH) | 2024-08-14 | — | — | EP | claimed |
| WO-2023094654-A1 | ACETOACETATE BASED KETALS | ARXADA AG (CH) | 2023-06-01 | — | — | WO | claimed |
| US-20250320175-A1 | Acetoacetate Based Ketals | ARXADA AG (CH) | 2025-10-16 | — | — | US | disclosed |
| WO-2025022405-A1 | MODULATORS OF A POTASSIUM CHANNEL AND OF TRPV1 CHANNEL AND USES THEREOF | BSENSE BIO THERAPEUTICS LTD. (IL) | 2025-01-30 | — | — | WO | disclosed |
| US-20250002446-A1 | Acetoacetate Based Ketals | ARXADA AG (CH) | 2025-01-02 | — | — | US | disclosed |
| EP-4412987-A1 | ACETOACETATE BASED KETALS | Arxada AG (CH) | 2024-08-14 | — | — | EP | disclosed |
| WO-2023126968-A1 | A PROCESS FOR THE SYNTHESIS OF BCX-1777 AND BCX-4430 | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2023-07-06 | — | — | WO | disclosed |
| WO-2023094654-A1 | ACETOACETATE BASED KETALS | ARXADA AG (CH) | 2023-06-01 | — | — | WO | disclosed |
| US-20090286873-A1 | AI-2 compounds and analogs based on Salmonella typhimurium LsrB structure | THE TRUSTEES OF PRINCETON UNIVERSITY | 2009-11-19 | — | — | US | disclosed |
| US-20090286873-A1 | AI-2 compounds and analogs based on Salmonella typhimurium LsrB structure | THE TRUSTEES OF PRINCETON UNIVERSITY | 2009-11-19 | — | — | US | disclosed |
| US-7547726-B2 | AI-2 compounds and analogs based on Salmonella typhimurium LsrB structure | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2009-06-16 | — | — | US | disclosed |
| WO-2005100384-A3 | AI-2 COMPOUNDS AND ANALOGS BASED ON SALMONELLA TYPHIMURIUM LSRB STRUCTURE | UNIV PRINCETON (US) | 2009-04-23 | — | — | WO | disclosed |
| US-20060229259-A1 | AI-2 compounds and analogs based on Salmonella typhimurium LsrB structure | NATIONAL INSTITUTES OF HEALTH | 2006-10-12 | — | — | US | disclosed |
| US-20060229259-A1 | AI-2 compounds and analogs based on Salmonella typhimurium LsrB structure | NATIONAL INSTITUTES OF HEALTH | 2006-10-12 | — | — | US | disclosed |
| US-20060063721-A1 | AI-2 compounds and analogs based on salmonella typhimurium LsrB structure | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-03-23 | — | — | US | disclosed |
| US-20060063721-A1 | AI-2 compounds and analogs based on salmonella typhimurium LsrB structure | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-03-23 | — | — | US | disclosed |
| WO-2005100384-A2 | AI-2 COMPOUNDS AND ANALOGS BASED ON SALMONELLA TYPHIMURIUM LSRB STRUCTURE | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2005-10-27 | — | — | WO | disclosed |
| WO-2005100384-A2 | AI-2 COMPOUNDS AND ANALOGS BASED ON SALMONELLA TYPHIMURIUM LSRB STRUCTURE | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2005-10-27 | — | — | WO | disclosed |