SCHEMBL386986

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL387586	0.87	PARP10 (0.50)	PARP10PARP1PARP11GRM5CDC7
	SCHEMBL4213794	0.85	PARP10 (0.49)	PARP10PARP1PARP11GRM5CDC7
	SCHEMBL27753698	0.85	PARP10 (0.52)	PARP10PARP1PARP11CDC7DBF4
	SCHEMBL393016	0.82	MAPKAPK2 (0.46)	PARP1GRM5CDC7DBF4MAPKAPK2
	SCHEMBL27749139	0.81	CHEK1 (0.40)	PARP10PARP1PARP11CDC7DBF4
	SCHEMBL793215	0.77	CDC7 (0.72)	PARP10PARP1PARP11GRM5CDC7
	SCHEMBL14053667	0.71	PARP10 (0.47)	PARP10PARP1PARP11GRM5PDPK1
	SCHEMBL27753699	0.71	PARP10 (0.47)	PARP10PARP1PARP11GRM5MAPKAPK2
	SCHEMBL3003038	0.71	HTR2C (0.44)	PARP1CDC7DBF4PDPK1IKBKB
	SCHEMBL797294	0.71	PARP10 (0.76)	PARP10PARP1PARP11GRM5MAPKAPK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.