⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL387270 | 1.00 | — | — | |
| SCHEMBL9457605 | 0.76 | — | — | |
| SCHEMBL387655 | 0.75 | — | — | |
| SCHEMBL387654 | 0.75 | — | — | |
| SCHEMBL387381 | 0.71 | — | — | |
| SCHEMBL387382 | 0.71 | — | — | |
| SCHEMBL5958320 | 0.71 | — | — | |
| SCHEMBL387704 | 0.68 | TSHR (0.42) | — | |
| SCHEMBL385957 | 0.68 | TSHR (0.42) | — | |
| SCHEMBL385815 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7598244-B2 | [1,2,4]triazolo[1,5,a]pyrimidin-2-ylurea derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2009-10-06 | — | — | US | claimed |
| US-12030868-B2 | Prodrugs of CGRP antagonists | PFIZER IRELAND PHARMACEUTICALS (IE) | 2024-07-09 | — | — | US | disclosed |
| US-20240067651-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | BIOHAVEN THERAPEUTICS LTD. | 2024-02-29 | — | — | US | disclosed |
| CN-114945573-A | Prodrugs of myeloperoxidase inhibitors | 拜奥海芬治疗学有限公司 | 2022-08-26 | — | — | CN | disclosed |
| US-20210395223-A1 | PRODRUGS OF CGRP ANTAGONISTS | PFIZER IRELAND PHARMACEUTICALS (IE) | 2021-12-23 | — | — | US | disclosed |
| EP-3863629-A1 | PRODRUGS OF CGRP ANTAGONISTS | Biohaven Pharmaceutical Holding Company Ltd. (US) | 2021-08-18 | — | — | EP | disclosed |
| CN-112888438-A | Prodrugs of CGRP antagonists | 拜尔哈文制药股份有限公司 | 2021-06-01 | — | — | CN | disclosed |
| WO-2021072140-A1 | PRODRUGS OF MYELOPEROXIDASE INHIBITORS | BIOHAVEN THERAPEUTICS LTD. (US) | 2021-04-15 | — | — | WO | disclosed |
| US-8802713-B2 | 3-alkoxy-1-phenylpyrazole derivatives and pesticides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-08-12 | — | — | US | disclosed |
| EP-2202226-B1 | 3-ALKOXY-1-PHENYLPYRAZOLE DERIVATIVE AND PEST CONTROL AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2013-06-05 | — | — | EP | disclosed |
| WO-1999029677-A1 | SUBSTITUTED 2,4-DIAMINO-1,3,5-TRIAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-06-17 | — | — | WO | disclosed |
| EP-0893421-A1 | ALKENYL COMPOUNDS, LIQUID CRYSTAL COMPOSITIONS, AND LIQUID CRYSTAL DISPLAY DEVICES | CHISSO CORPORATION (JP) | 1999-01-27 | — | — | EP | disclosed |
| EP-0885875-A1 | VINYLENE COMPOUNDS AND LIQUID-CRYSTAL COMPOSITION | CHISSO CORPORATION (JP) | 1998-12-23 | — | — | EP | disclosed |
| EP-0872484-A1 | ORGANOSILICON COMPOUNDS, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 1998-10-21 | — | — | EP | disclosed |
| EP-0430001-B1 | Process for preparing benzaldehydes | BAYER AG (DE) | 1993-12-22 | — | — | EP | disclosed |
| US-5082976-A | PROCESS FOR THE PREPARATION OF BENZALDEHYDES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-21 | — | — | US | disclosed |
| EP-0430001-A1 | Process for preparing benzaldehydes | BAYER AG (DE) | 1991-06-05 | — | — | EP | disclosed |
| EP-0192242-B1 | SUBSTITUTED AMINOPHENYLUREA DERIVATIVES | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1990-11-07 | — | — | EP | disclosed |
| US-4803223-A | ANTITUMOR AGENTS | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1989-02-07 | — | — | US | disclosed |
| EP-0192242-A1 | Substituted aminophenylurea derivatives | TOKUYAMA SODA KABUSHIKI KAISHA (JP) | 1986-08-27 | — | — | EP | disclosed |