Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.34 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.34 |
| ▸ | CHRNG | P07510 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CHRND | Q07001 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834344 | 1.00 | NPSR1 (0.42) | NPSR1ALDH1A1GUSBHTTLMNA | |
| SCHEMBL3834348 | 1.00 | NPSR1 (0.42) | NPSR1ALDH1A1GUSBHTTLMNA | |
| SCHEMBL1508961 | 1.00 | NPSR1 (0.42) | NPSR1ALDH1A1GUSBHTTLMNA | |
| SCHEMBL4204488 | 1.00 | NPSR1 (0.42) | NPSR1ALDH1A1GUSBHTTLMNA | |
| SCHEMBL13567925 | 0.93 | CNR1 (0.41) | NPSR1ALDH1A1GUSBHTTLMNA | |
| SCHEMBL13567928 | 0.93 | CNR1 (0.41) | NPSR1ALDH1A1GUSBHTTLMNA | |
| SCHEMBL13568024 | 0.93 | CNR1 (0.41) | NPSR1ALDH1A1GUSBHTTLMNA | |
| SCHEMBL13567903 | 0.93 | CNR1 (0.41) | NPSR1ALDH1A1GUSBHTTLMNA | |
| SCHEMBL3827176 | 0.92 | NPSR1 (0.45) | NPSR1ALDH1A1GUSBLMNAKMT2A | |
| SCHEMBL3847881 | 0.92 | NPSR1 (0.48) | NPSR1ALDH1A1LMNAKMT2AALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2103619-A1 | IMIDAZOTHIAZOLE DERIVATIVES | Daiichi Sankyo Company, Limited (JP) | 2009-09-23 | — | — | EP | disclosed |