Valnoctamide

Valnoctamide

SCHEMBL387435

CCC(C)C(CC)C(N)=O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA7 P43166 2/20 0.39
CA14 Q9ULX7 2/20 0.39
DPP4 P27487 3/20 0.35
DPP8 Q6V1X1 2/20 0.35
DPP9 Q86TI2 2/20 0.35
ACE P12821 4/20 0.35
ALDH1A1 P00352 1/20 0.33
EPHX1 P07099 1/20 0.33
MME P08473 2/20 0.32
CPA1 P15085 2/20 0.32
ACE2 Q9BYF1 2/20 0.32
ENPEP Q07075 2/20 0.32
TSHR P16473 1/20 0.32
DPP7 Q9UHL4 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Valnoctamide SCHEMBL5053817 1.00 CA1 (0.39) CA1CA2CA7CA14DPP4
SCHEMBL20259104 0.85 CA1 (0.35) CA1CA2CA7CA14DPP4
SCHEMBL7511543 0.85 CA1 (0.35) CA1CA2CA7CA14EPHX1
SCHEMBL277889 0.83 CA1 (0.43) CA1CA2CA7CA14ALDH1A1
(2R,3S)-Sec-Butylpropylacetamide SCHEMBL24621638 0.83 CA1 (0.43) CA1CA2CA7CA14DPP4
SCHEMBL8314806 0.83 CA1 (0.34) CA1CA2CA7CA14DPP4
SCHEMBL12015470 0.83 ACE (0.38) CA1CA2CA7CA14DPP4
SCHEMBL3504203 0.83 ECE1 (0.38) CA1CA2CA7CA14DPP4
(2R,3S)-Sec-Butylpropylacetamide SCHEMBL1577854 0.83 CA1 (0.43) CA1CA2CA7CA14DPP4
(2R,3S)-Sec-Butylpropylacetamide SCHEMBL25669842 0.83 CA1 (0.43) CA1CA2CA7CA14DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4687835-A1 A BIPHASIC LIQUID PHARMACEUTICAL COMPOSITION OF AN ANTICONVULSANT DRUG AND THE PROCESS OF PREPARING THE SAME Orbit Pharma Limited (GB) 2026-02-11 EP claimed
EP-3518975-B1 FORMULATION COMPRISING FENFLURAMINE AND CANNABIDIOL AND ITS USE IN THE TREATMENT OF SEIZURES ZOGENIX INTERNATIONAL LTD (GB) 2025-04-09 EP claimed
WO-2024201019-A1 A BIPHASIC LIQUID PHARMACEUTICAL COMPOSITION OF AN ANTICONVULSANT DRUG AND THE PROCESS OF PREPARING THE SAME ORBIT PHARMA LIMITED (GB) 2024-10-03 WO claimed
US-11786487-B2 Formulation for inhibiting formation of 5-HT2B agonists and methods of using same ZOGENIX INTERNATIONAL LIMITED (GB) 2023-10-17 US claimed
WO-2023178250-A1 TREATMENT OF TUBEROUS SCLEROSIS WITH MIRDAMETINIB SpringWorks Therapeutics Inc. (US) 2023-09-21 WO claimed
US-11759440-B2 Formulation for inhibiting formation of 5-HT2B agonists and methods of using same ZOGENIX INTERNATIONAL LIMITED (GB) 2023-09-19 US claimed
US-20220378782-A1 KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) 2022-12-01 US claimed
US-20210393550-A1 Formulation for Inhibiting Formation of 5-HT2B Agonists and Methods of Using Same ZOGENIX INTERNATIONAL LIMITED (GB) 2021-12-23 US claimed
US-11040018-B2 Formulation for inhibiting formation of 5-HT2B agonists and methods of using same ZOGENIX INTERNATIONAL LIMITED (GB) 2021-06-22 US claimed
US-20200246281-A1 Formulation for Inhibiting Formation of 5-HT2B Agonists and Methods of Using Same ZOGENIX INTERNATIONAL LIMITED (GB) 2020-08-06 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060004098-A1 Compounds useful for treating neurological disorders YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2006-01-05 US claimed
WO-2005009430-A1 COMPOUNDS USEFUL FOR TREATING NEUROLOGICAL DISORDERS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2005-02-03 WO claimed
US-20030212131-A1 Propylisopropyl acetic acid and propylisopropyl acetamide stereoisomers, a method for their synthesis and pharmaceutical compositions containing them BIALER MEIR (IL) 2003-11-13 US claimed
EP-0966429-B1 VALNOCTAMIDE STEREOISOMERS, A METHOD FOR THEIR SYNTHESIS AND SEPARATION AND USES THEREOF YISSUM RES DEV CO (IL) 2003-06-04 EP claimed
EP-1273301-A2 Pharmaceutical preparations based on active ingredients susceptible to illicit administration ALTERGON S.A. (CH) 2003-01-08 EP claimed
US-6417399-B1 ETHYLATION OF ISOLEUCINE TO 3-METHYLVALERIC ACID; HALOACYLATION TO METHYL VALEROYL CHLORIDE; CARBOXYLATION TO VALNOCTIC ACID; AMIDATION TO VALNOCTAMIDE; ANTIEPILEPTIC AGENTS; PSYCHOLOGICAL DISORDERS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2002-07-09 US claimed
EP-0966429-A1 VALNOCTAMIDE STEREOISOMERS, A METHOD FOR THEIR SYNTHESIS AND SEPARATION AND USES THEREOF YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1999-12-29 EP claimed
WO-1998030536-A1 VALNOCTAMIDE STEREOISOMERS, A METHOD FOR THEIR SYNTHESIS AND SEPARATION AND USES THEREOF YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 1998-07-16 WO claimed
US-4557934-A ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE THE PROCTER & GAMBLE COMPANY (US) 1985-12-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200246281-A1 Formulation for Inhibiting Formation of 5-HT2B Agonists and Methods of Using Same HTR2B, HTR1B, CYP4B1 CA1 4608/4885CA2 4148/4885CA7 4785/4885
US-20030212131-A1 Propylisopropyl acetic acid and propylisopropyl acetamide stereoisomers, a method for their synthesis and pharmaceutical compositions containing them ADCYAP1R1, GRIN2A, PTGER1 CA1 1049/4885CA2 1385/4885CA7 2706/4885
US-20060004098-A1 Compounds useful for treating neurological disorders GAP43, CLN6, NLN CA1 2293/4885CA2 2362/4885CA7 4002/4885
US-11040018-B2 Formulation for inhibiting formation of 5-HT2B agonists and methods of using same HTR2B, HTR1B, CYP4B1 CA1 4608/4885CA2 4148/4885CA7 4785/4885
US-11759440-B2 Formulation for inhibiting formation of 5-HT2B agonists and methods of using same HTR2B, HTR1B, CYP4B1 CA1 4608/4885CA2 4148/4885CA7 4785/4885
US-11786487-B2 Formulation for inhibiting formation of 5-HT2B agonists and methods of using same HTR2B, HTR1B, CYP4B1 CA1 4608/4885CA2 4148/4885CA7 4785/4885
US-20220378782-A1 KCC2 EXPRESSION ENHANCING COMPOUNDS AND USES THEREOF MECP2, SLC1A2, GRIN2C CA1 2398/4885CA2 1281/4885CA7 4265/4885
US-20210393550-A1 Formulation for Inhibiting Formation of 5-HT2B Agonists and Methods of Using Same HTR2B, HTR1B, CYP4B1 CA1 4608/4885CA2 4148/4885CA7 4785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.