Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 19/20 | 0.64 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3876817 | 1.00 | DHODH (0.64) | DHODHMMP2MMP3 | |
| SCHEMBL3878495 | 0.88 | DHODH (0.66) | DHODH | |
| SCHEMBL3873445 | 0.86 | DHODH (0.64) | DHODH | |
| SCHEMBL729529 | 0.80 | DHODH (1.00) | DHODH | |
| SCHEMBL1955242 | 0.80 | DHODH (0.78) | DHODH | |
| SCHEMBL729535 | 0.79 | DHODH (0.84) | DHODH | |
| SCHEMBL727460 | 0.78 | DHODH (0.83) | DHODH | |
| SCHEMBL3871702 | 0.78 | DHODH (0.58) | DHODH | |
| SCHEMBL729155 | 0.78 | DHODH (0.75) | DHODH | |
| SCHEMBL3729833 | 0.78 | DHODH (0.75) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121614-A1 | AMINO NICOTINIC AND ISONICOTINIC ACID DERIVATIVES AS DHODH INHIBITORS | Almirall, S.A. (ES) | 2009-11-25 | — | — | EP | claimed |
| WO-2008077639-A1 | AMINO NICOTINIC AND ISONICOTINIC ACID DERIVATIVES AS DHODH INHIBITORS | LABORATORIOS ALMIRALL, S.A. (ES) | 2008-07-03 | — | — | WO | claimed |