Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3874386 | 0.94 | DHODH (0.58) | DHODH | |
| SCHEMBL3871702 | 0.78 | DHODH (0.58) | DHODH | |
| SCHEMBL3873079 | 0.75 | DHODH (0.56) | DHODH | |
| SCHEMBL3871553 | 0.74 | DHODH (0.55) | DHODH | |
| SCHEMBL727801 | 0.74 | DHODH (0.61) | DHODH | |
| SCHEMBL13974154 | 0.72 | DHODH (0.80) | DHODH | |
| SCHEMBL3877118 | 0.72 | DHODH (0.61) | DHODH | |
| SCHEMBL3877813 | 0.72 | DHODH (0.61) | DHODH | |
| SCHEMBL3872950 | 0.71 | DHODH (0.69) | DHODH | |
| SCHEMBL729540 | 0.71 | DHODH (1.00) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121614-A1 | AMINO NICOTINIC AND ISONICOTINIC ACID DERIVATIVES AS DHODH INHIBITORS | Almirall, S.A. (ES) | 2009-11-25 | — | — | EP | claimed |
| WO-2008077639-A1 | AMINO NICOTINIC AND ISONICOTINIC ACID DERIVATIVES AS DHODH INHIBITORS | LABORATORIOS ALMIRALL, S.A. (ES) | 2008-07-03 | — | — | WO | claimed |