⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3875730 | 0.81 | SLC7A5 (0.46) | — | |
| SCHEMBL3381845 | 0.80 | SLC7A5 (0.39) | — | |
| SCHEMBL583792 | 0.77 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL583793 | 0.77 | SMN1; SMN2 (0.46) | — | |
| SCHEMBL3381189 | 0.75 | SLC7A5 (0.34) | — | |
| SCHEMBL3947984 | 0.74 | — | — | |
| SCHEMBL3947980 | 0.74 | — | — | |
| SCHEMBL7058341 | 0.74 | — | — | |
| SCHEMBL10655128 | 0.73 | GSR (0.48) | — | |
| SCHEMBL10656950 | 0.73 | GSR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2120555-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | Heller, Adam (US) | 2009-11-25 | — | — | EP | claimed |
| US-20080287866-A1 | Methods and compositions for the treatment of pain | HELLER ADAM | 2008-11-20 | — | — | US | claimed |
| WO-2008094664-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2008-08-07 | — | — | WO | claimed |
| CN-112292123-A | Succinic acid and derivatives for the treatment of hematological disorders | 恩泽生物科学有限公司 | 2021-01-29 | — | — | CN | disclosed |
| US-20080287866-A1 | Methods and compositions for the treatment of pain | HELLER ADAM | 2008-11-20 | — | — | US | disclosed |