Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | KLK1 | P06870 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3879157 | 0.95 | F10 (0.46) | F10TP53F2KLK1 | |
| SCHEMBL3875017 | 0.86 | F10 (0.49) | F10TP53F2KLK1 | |
| SCHEMBL219860 | 0.86 | F10 (0.65) | F10TP53 | |
| SCHEMBL3874943 | 0.84 | F10 (0.43) | F10F2KLK1 | |
| SCHEMBL3876204 | 0.84 | F10 (0.42) | F10F2KLK1 | |
| SCHEMBL3872604 | 0.83 | F10 (0.42) | F10F2KLK1 | |
| SCHEMBL3875244 | 0.82 | F10 (0.52) | F10F2KLK1 | |
| SCHEMBL3877246 | 0.81 | F10 (0.43) | F10F2 | |
| SCHEMBL221251 | 0.81 | F10 (0.63) | F10 | |
| SCHEMBL3873911 | 0.80 | F10 (0.72) | F10F2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888567-B1 | HETEROARYL-CARBOXYLIC ACID (SULFAMOYL ALKYL) AMIDE - DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI AVENTIS (FR) | 2009-12-16 | — | — | EP | claimed |