SCHEMBL3875802

SCHEMBL3875802

Cc1cccc(NCCO)c1C

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.60
MAPT P10636 5/20 0.53
GAA P10253 3/20 0.53
TP53 P04637 2/20 0.53
MAPK1 P28482 2/20 0.53
HSD17B10 Q99714 2/20 0.53
HTT P42858 1/20 0.52
BRD4 O60885 1/20 0.49
KEAP1 Q14145 1/20 0.48
NFE2L2 Q16236 1/20 0.48
KDM4E B2RXH2 1/20 0.46
GLA P06280 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALDH1A1 P00352 3/20 0.45
HPGD P15428 1/20 0.45
ALOX15 P16050 1/20 0.45
RAPGEF4 Q8WZA2 1/20 0.43
HDAC3 O15379 1/20 0.42
HDAC4 P56524 1/20 0.42
HDAC1 Q13547 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34077 0.90 KDM4E (0.50) KMT2AMAPTGAATP53MAPK1
SCHEMBL26928986 0.89 KMT2A (0.53) KMT2AMAPTGAATP53MAPK1
SCHEMBL11170519 0.87 MAPT (0.67) KMT2AMAPTGAATP53MAPK1
SCHEMBL29589735 0.83 MAPT (0.75) KMT2AMAPTGAAMAPK1HTT
SCHEMBL56497 0.83 MAPT (0.75) KMT2AMAPTGAAMAPK1HTT
SCHEMBL10453654 0.83 MAPT (0.56) KMT2AMAPTGAATP53MAPK1
SCHEMBL18684664 0.83 MAPT (0.56) KMT2AMAPTGAATP53MAPK1
SCHEMBL4050173 0.82 MAPT (0.50) KMT2AMAPTGAATP53MAPK1
SCHEMBL5241332 0.82 MAPT (0.50) KMT2AMAPTGAAHSD17B10HTT
SCHEMBL453906 0.82 MAPT (0.47) KMT2AMAPTGAATP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100577135-C Dental polymerizable core build-up material of separately packed type KURARAY MEDICAL INC 2010-01-06 CN claimed
EP-2032622-A1 FAST-CURING CHEMICAL FASTENING SYSTEM AND USE THEREOF fischerwerke GmbH & Co. KG (DE) 2009-03-11 EP claimed
WO-2008000452-A1 FAST-CURING CHEMICAL FASTENING SYSTEM AND USE THEREOF FISCHERWERKE GMBH & CO. KG (DE) 2008-01-03 WO claimed
CN-118620030-A Taxol derivative modified based on zwitterionic polypeptide, prodrug nano drug-loaded micelle and preparation method thereof 燕山大学 2024-09-10 CN disclosed
CN-117003820-A Thiol-containing zwitterionic polypeptide modified degradable amphiphilic molecule, nano micelle and preparation method thereof 燕山大学 2023-11-07 CN disclosed
EP-3466920-A1 METHOD FOR OBTAINING -AMINO ALCOHOLS Universitat de València (ES) 2019-04-10 EP disclosed
EP-3365383-A1 SYNTHETIC FIXING SYSTEM CONTAINING VINYLESTER URETHANES SUCH AS URETHANE(METH)ACRYLATE BASED ON RENEWABLE RAW MATERIALS fischerwerke GmbH & Co. KG (DE) 2018-08-29 EP disclosed
EP-3344721-A1 CORROSION-INHIBITING, RADICALLY CUREABLE COMPOSITION Sika Technology AG (CH) 2018-07-11 EP disclosed
EP-3303438-A1 VINYL-TERMINATED PREPOLYMERS HAVING LOW VISCOSITY AND GOOD WATER SOLUBILITY Sika Technology AG (CH) 2018-04-11 EP disclosed
CN-102947243-B The reinforcing mortar of free redical polymerization with silane additives 费希尔厂有限责任两合公司 2017-09-05 CN disclosed
CN-102947243-A Free-radically polymerisable fastening mortar having silane additives FISCHERWERKE GMBH & CO KG 2013-02-27 CN disclosed
EP-1379570-A1 VINYLESTER CARBAMIDE fischerwerke Artur Fischer GmbH & Co. KG (DE) 2004-01-14 EP disclosed
EP-1373429-A1 MULTI-COMPONENT KITS AND COMBINATIONS, USE THEREOF AND PLASTIC CEMENTS OBTAINED THEREFROM fischerwerke Artur Fischer GmbH & Co. KG (DE) 2004-01-02 EP disclosed
WO-2002079293-A1 VINYLESTER CARBAMIDE FISCHERWERKE ARTUR FISCHER GMBH & CO. KG (DE) 2002-10-10 WO disclosed
WO-2002079341-A1 MULTI-COMPONENT KITS AND COMBINATIONS, USE THEREOF AND PLASTIC CEMENTS OBTAINED THEREFROM FISCHERWERKE ARTUR FISCHER GMBH & CO. KG (DE) 2002-10-10 WO disclosed
CN-1181751-A Prepn. of N-arylmethyl axiridine derivatives, 1, 4, 7, 10 -Tetraazacyclododecane derivatives obtained therefrom and N -arylmethyl -ethanol -amine sulphonate esters as intermediates NYCOMED SALUTAR INC (US) 1998-05-13 CN disclosed
EP-0589831-B1 Mortar and device for fixing of anchoring means in bore holes HILTI AG (LI) 1996-10-23 EP disclosed
EP-0589831-A1 Mortar and device for fixing of anchoring means in bore holes HILTI Aktiengesellschaft (LI) 1994-03-30 EP disclosed
US-4308190-A Dental materials based on organic plastics in paste form BAYER AKTIENGESELLSCHAFT (DE) 1981-12-29 US disclosed
US-4223138-A VAPORIZATION, CONDENSATION, RETARDING FLOW TO REACTION ZONE BAYER AKTIENGESELLSCHAFT (DE) 1980-09-16 US disclosed