Pharacine

Pharacine

SCHEMBL3876076

O=C1OCCCCOC(=O)c2ccc(cc2)C(=O)OCCCCOC(=O)c2ccc1cc2

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.42
CA9 Q16790 1/20 0.42
NAMPT P43490 1/20 0.37
ALDH1A1 P00352 3/20 0.34
CLK1 P49759 2/20 0.34
DYRK1A Q13627 2/20 0.34
DYRK1B Q9Y463 2/20 0.34
KMT2A Q03164 4/20 0.33
MAPT P10636 2/20 0.33
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
MEN1 O00255 2/20 0.31
POLB P06746 2/20 0.31
PTGS1 P23219 1/20 0.31
HSP90AA1 P07900 1/20 0.31
HSP90AB1 P08238 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28713686 1.00 CA1 (0.42) CA1CA9NAMPTALDH1A1CLK1
SCHEMBL3873588 1.00 CA1 (0.42) CA1CA9NAMPTALDH1A1CLK1
SCHEMBL36010 1.00 CA1 (0.42) CA1CA9NAMPTALDH1A1CLK1
SCHEMBL28704246 1.00 CA1 (0.42) CA1CA9NAMPTALDH1A1CLK1
SCHEMBL4157033 0.97 CA1 (0.40) CA1CA9NAMPTALDH1A1CLK1
SCHEMBL3174046 0.97 CA1 (0.40) CA1CA9NAMPTALDH1A1CLK1
SCHEMBL2483184 0.97 CA1 (0.40) CA1CA9NAMPTALDH1A1CLK1
SCHEMBL197445 0.97 CA1 (0.40) CA1CA9NAMPTALDH1A1CLK1
SCHEMBL597282 0.97 CA1 (0.40) CA1CA9NAMPTALDH1A1CLK1
SCHEMBL28580296 0.97 CA1 (0.40) CA1CA9NAMPTALDH1A1CLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114249973-B Polybutylene terephthalate composition 长春人造树脂厂股份有限公司 2023-08-08 CN disclosed
CN-115340980-B Culture medium synergist and application thereof in promoting umbilical mesenchymal stem cells to repair photoaged skin 广东瑞程医学科技有限公司 2023-08-01 CN disclosed
US-11548245-B2 Fiber-containing prepregs and methods and systems of making JOHNS MANVILLE (US) 2023-01-10 US disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 US disclosed
CN-114249973-A Polybutylene terephthalate composition 长春人造树脂厂股份有限公司 2022-03-29 CN disclosed
US-11231906-B2 Manufacturing thermoplastic composites and articles JOHNS MANVILLE (US) 2022-01-25 US disclosed
EP-2813538-B1 Method for making a prepreg and fiber-reinforced composite article JOHNS MANVILLE (US) 2021-12-29 EP disclosed
US-20210397410-A9 MANUFACTURING THERMOPLASTIC COMPOSITES AND ARTICLES JOHNS MANVILLE 2021-12-23 US disclosed
EP-2876133-B1 Fiber-containing prepregs and methods and systems of making JOHNS MANVILLE (US) 2021-02-17 EP disclosed
US-10780609-B2 Fiber-reinforced composite articles and methods of making them Jonhs Manville (US) 2020-09-22 US disclosed
WO-2008106572-A1 PROCESS AND PERFORMANCE AID FOR CARBON NANOTUBES ARKEMA INC. (US) 2008-09-04 WO disclosed
EP-1896482-A2 ENZYME-CATALYZED PROCESS FOR THE PREPARATION OF MACROCYCLIC POLYESTER OLIGOMERS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2008-03-12 EP disclosed
US-20070021584-A1 Enzyme-catalyzed process for the preparation of macrocyclic polyester oligomers E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-25 US disclosed
US-20070021584-A1 Enzyme-catalyzed process for the preparation of macrocyclic polyester oligomers E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-25 US disclosed
US-20070021584-A1 Enzyme-catalyzed process for the preparation of macrocyclic polyester oligomers E. I. DU PONT DE NEMOURS AND COMPANY 2007-01-25 US disclosed
WO-2006133332-A2 ENZYME-CATALYZED PROCESS FOR THE PREPARATION OF MACROCYCLIC POLYESTER OLIGOMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-12-14 WO disclosed
US-7026433-B2 Continuous bioreactor process for the preparation of polyester cyclic oligomers E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-04-11 US disclosed
EP-1618138-A2 CONTINUOUS BIOREACTOR PROCESS FOR THE PREPARATION OF POLYESTER CYCLIC OLIGOMERS E.I. du Pont de Nemours and Company (US) 2006-01-25 EP disclosed
US-20050054809-A1 Continuous bioreactor process for the preparation of polyester cyclic oligomers E. I. DU PONT DE NEMOURS AND COMPANY 2005-03-10 US disclosed
WO-2004099174-A2 CONTINUOUS BIOREACTOR PROCESS FOR THE PREPARATION OF POLYESTER CYCLIC OLIGOMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-11-18 WO disclosed