Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 9/20 | 0.62 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | CCR3 | P51677 | 5/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2956247 | 0.85 | SSTR5 (0.69) | SSTR5CCR3KCNH2 | |
| SCHEMBL2965998 | 0.79 | SSTR5 (0.72) | SSTR5CCR3KCNH2 | |
| SCHEMBL2957516 | 0.79 | SSTR5 (0.75) | SSTR5CCR3HTR7KCNH2 | |
| SCHEMBL2956220 | 0.78 | SSTR5 (0.66) | SSTR5CCR3KCNH2 | |
| SCHEMBL2951998 | 0.77 | SSTR5 (0.83) | SSTR5CCR3KCNH2 | |
| SCHEMBL2954083 | 0.77 | SSTR5 (0.83) | SSTR5CCR3KCNH2 | |
| SCHEMBL2955285 | 0.77 | SSTR5 (0.69) | SSTR5CCR3KCNH2 | |
| SCHEMBL2955622 | 0.77 | SSTR5 (1.00) | SSTR5KCNH2 | |
| SCHEMBL2963832 | 0.76 | SSTR5 (0.73) | SSTR5CCR3KCNH2 | |
| SCHEMBL2954887 | 0.76 | SSTR5 (0.84) | SSTR5CCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893603-B1 | PIPERIDIN-4-YL-AMIDE DERIVATIVES AND THEIR USE AS SST RECEPTOR SUBTYPE 5 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2009-10-14 | — | — | EP | disclosed |