Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 11/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2249003 | 1.00 | CHRM4 (0.46) | CHRM4TP53MAPTALOX15MAPK1 | |
| SCHEMBL2550208 | 1.00 | CHRM4 (0.46) | CHRM4TP53MAPTALOX15MAPK1 | |
| SCHEMBL2247219 | 0.88 | CHRM2 (0.51) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL2549773 | 0.84 | KCNA5 (0.44) | CHRM4MAPTALOX15MAPK1KCNA5 | |
| SCHEMBL2246813 | 0.84 | KCNA5 (0.44) | CHRM4MAPTALOX15MAPK1KCNA5 | |
| SCHEMBL1827654 | 0.80 | PPARA (0.43) | — | |
| SCHEMBL1824528 | 0.79 | KMT2A (0.47) | MAPTSMN1; SMN2CHRM1HTT | |
| SCHEMBL2245212 | 0.76 | GRM5 (0.42) | TP53MAPTALOX15MAPK1SMN1; SMN2 | |
| SCHEMBL13876582 | 0.76 | MAPT (0.41) | MAPTSMN1; SMN2HTT | |
| SCHEMBL2244594 | 0.76 | CA12 (0.46) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771421-B1 | N-HYDROXYAMIDE DERIVATIVES AND USE THEREOF | SERONO LAB (CH) | 2009-04-29 | — | — | EP | claimed |