Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 11/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3878956 | 0.95 | MALT1 (0.38) | MALT1TRPV1CHRM4DYRK1AMAP3K12 | |
| SCHEMBL3879062 | 0.93 | TRPV1 (0.43) | MALT1TRPV1CHRM4DYRK1A | |
| SCHEMBL3875754 | 0.93 | TRPV1 (0.37) | MALT1TRPV1CHRM4DYRK1AMAP3K12 | |
| SCHEMBL3879145 | 0.92 | TRPV1 (0.47) | MALT1TRPV1CHRM4MAP3K12 | |
| SCHEMBL3883287 | 0.92 | TRPV1 (0.47) | MALT1TRPV1CHRM4MAP3K12 | |
| SCHEMBL3877385 | 0.92 | TRPV1 (0.47) | MALT1TRPV1CHRM4MAP3K12 | |
| SCHEMBL3889730 | 0.92 | TRPV1 (0.47) | MALT1TRPV1CHRM4MAP3K12 | |
| SCHEMBL3883422 | 0.92 | TRPV1 (0.47) | MALT1TRPV1CHRM4MAP3K12 | |
| SCHEMBL3941459 | 0.92 | TRPV1 (0.47) | MALT1TRPV1CHRM4MAP3K12 | |
| SCHEMBL3879150 | 0.92 | TRPV1 (0.47) | MALT1TRPV1CHRM4MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566712-B2 | Biaryl piperazinyl-pyridine analogues | NEUROGEN CORPORATION (US) | 2009-07-28 | — | — | US | disclosed |
| US-7566712-B2 | Biaryl piperazinyl-pyridine analogues | NEUROGEN CORPORATION (US) | 2009-07-28 | — | — | US | disclosed |
| US-7566712-B2 | Biaryl piperazinyl-pyridine analogues | NEUROGEN CORPORATION (US) | 2009-07-28 | — | — | US | disclosed |