SCHEMBL387893

SCHEMBL387893

C=CC[Si](Cl)(Cl)OCCC

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL388512 0.87 TSHR (0.36) TSHR
SCHEMBL390270 0.82 TSHR (0.31) TSHR
SCHEMBL384518 0.81
SCHEMBL388974 0.81
SCHEMBL384517 0.81
SCHEMBL459676 0.77
SCHEMBL459675 0.77
SCHEMBL15303052 0.76 TSHR (0.33) TSHR
SCHEMBL3338598 0.76 TSHR (0.33) TSHR
SCHEMBL385400 0.76 TSHR (0.33) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101697-B2 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2012-01-24 US claimed
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2006-08-03 US claimed
EP-1883658-B2 METHOD FOR PREPARING LOW MOLECULAR WEIGHT POLYMERS BRIDGESTONE CORP (JP) 2016-01-27 EP disclosed
US-8101697-B2 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2012-01-24 US disclosed
US-8058351-B2 Method for preparing low molecular weight polymers BRIDGESTONE CORPORATION (JP) 2011-11-15 US disclosed
EP-1883658-B1 METHOD FOR PREPARING LOW MOLECULAR WEIGHT POLYMERS BRIDGESTONE CORP (JP) 2011-08-03 EP disclosed
US-20090105423-A1 Method for preparing low molecular weight polymers BRIDGESTONE CORPORATION (JP) 2009-04-23 US disclosed
EP-1883658-A1 METHOD FOR PREPARING LOW MOLECULAR WEIGHT POLYMERS Bridgestone Corporation (JP) 2008-02-06 EP disclosed
WO-2006127483-A1 METHOD FOR PREPARING LOW MOLECULAR WEIGHT POLYMERS BRIDGESTONE CORPORATION (JP) 2006-11-30 WO disclosed
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers BRIDGESTONE CORPORATION (JP) 2006-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060173145-A1 Multi-functionalized high-trans elastomeric polymers VCL, PUF60, JMJD6 TSHR 4359/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.