Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 10/20 | 0.41 |
| ▸ | KDR | P35968 | 10/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3874891 | 0.99 | AURKA (0.41) | AURKAKDRCDK1PARP1FFAR1 | |
| Hydrochloric Acid SCHEMBL3836110 | 0.87 | AURKA (0.48) | AURKAKDRCDK1PARP1FFAR1 | |
| SCHEMBL3877283 | 0.84 | AURKA (0.40) | AURKAKDRCDK1PARP1MAPT | |
| Hydrochloric Acid SCHEMBL3874897 | 0.83 | AURKA (0.40) | AURKAKDRCDK1PARP1MAPT | |
| SCHEMBL3855996 | 0.81 | KDR (0.42) | AURKAKDRCDK1PARP1FFAR1 | |
| Hydrochloric Acid SCHEMBL3860986 | 0.80 | KDR (0.41) | AURKAKDRCDK1PARP1FFAR1 | |
| Hydrochloric Acid SCHEMBL3839621 | 0.80 | KDR (0.46) | AURKAKDRCDK1PARP1KDM4E | |
| SCHEMBL3835222 | 0.80 | KDR (0.62) | AURKAKDRCDK1PARP1KDM4E | |
| Hydrochloric Acid SCHEMBL3874594 | 0.79 | CHEK1 (0.49) | AURKAKDRCDK1PARP1 | |
| Hydrochloric Acid SCHEMBL3856617 | 0.76 | AURKA (0.51) | AURKAKDRCDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108642-A1 | JAK INHIBITOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-10-14 | — | — | EP | disclosed |