SCHEMBL3882373

SCHEMBL3882373

COC(=O)CCc1ccc(OCC2CCCC2)c(-c2ccc3cc(NC(C)=O)ccc3c2)c1

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
C5AR1 P21730 3/20 0.45
SRC P12931 4/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.38
CCR5 P51681 1/20 0.37
DHODH Q02127 1/20 0.37
HRH3 Q9Y5N1 1/20 0.37
ABL1 P00519 1/20 0.36
CCNC P24863 1/20 0.36
CDK8 P49336 1/20 0.36
PTPN1 P18031 1/20 0.36
FFAR4 Q5NUL3 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3883137 0.92 C5AR1 (0.49) C5AR1SRCMEN1KMT2ANPSR1
SCHEMBL3882832 0.92 C5AR1 (0.46) C5AR1SRCMEN1KMT2ACCR5
SCHEMBL3887867 0.91 C5AR1 (0.42) C5AR1SRCMEN1KMT2ANPSR1
SCHEMBL3893938 0.90 SMN1; SMN2 (0.42) C5AR1SRCMEN1KMT2ANPSR1
SCHEMBL3883719 0.88 CCNC (0.48) C5AR1SRCMEN1KMT2AHRH3
SCHEMBL3676519 0.88 C5AR1 (0.40) C5AR1SRCMEN1KMT2AHRH3
SCHEMBL3892064 0.88 SMN1; SMN2 (0.41) C5AR1SRCMEN1KMT2ANPSR1
SCHEMBL3895660 0.88 C5AR1 (0.41) C5AR1SRCMEN1KMT2ANPSR1
SCHEMBL3681581 0.87 MEN1 (0.41) C5AR1SRCMEN1KMT2ADHODH
SCHEMBL3680727 0.87 C5AR1 (0.41) C5AR1SRCMEN1KMT2AHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1477472-B1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORP (JP) 2009-01-14 EP claimed
US-6867320-B2 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2005-03-15 US claimed
EP-1477472-A1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2004-11-17 EP claimed
US-20040044258-A1 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2004-03-04 US claimed
EP-1477472-B1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF ASAHI KASEI PHARMA CORP (JP) 2009-01-14 EP disclosed
US-6867320-B2 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2005-03-15 US disclosed
EP-1477472-A1 SUBSTITUTED PHENYLALKANOIC ACID DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2004-11-17 EP disclosed
US-20040044258-A1 Substituted phenylalkanoic acid derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2004-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040044258-A1 Substituted phenylalkanoic acid derivatives and use thereof PTGER1, CYSLTR1, PTGS1 C5AR1 282/4885SRC 3603/4885MEN1 4756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.