Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 8/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.54 |
| ▸ | MAP2 | P11137 | 4/20 | 0.54 |
| ▸ | KIT | P10721 | 4/20 | 0.52 |
| ▸ | FLT3 | P36888 | 3/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.49 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.44 |
| ▸ | FYN | P06241 | 2/20 | 0.44 |
| ▸ | CSF1R | P07333 | 2/20 | 0.44 |
| ▸ | LYN | P07948 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | FLT1 | P17948 | 2/20 | 0.44 |
| ▸ | FLT4 | P35916 | 2/20 | 0.44 |
| ▸ | BLK | P51451 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13761324 | 0.87 | KDR (0.53) | STING1KDRPDGFRBMAP2GAA | |
| SCHEMBL3883640 | 0.86 | MAP2 (0.63) | STING1KDRPDGFRBMAP2KIT | |
| SCHEMBL3884472 | 0.86 | MAP2 (0.63) | STING1KDRPDGFRBMAP2KIT | |
| SCHEMBL3882131 | 0.85 | MAP2 (0.56) | KDRPDGFRBMAP2MAPTNPC1 | |
| SCHEMBL3879349 | 0.85 | KDR (0.73) | KDRPDGFRBMAP2KITFLT3 | |
| SCHEMBL3878470 | 0.85 | MAP2 (0.56) | KDRPDGFRBMAP2KITFLT3 | |
| SCHEMBL3877984 | 0.85 | KDR (0.75) | KDRPDGFRBMAP2KITFLT3 | |
| SCHEMBL3883071 | 0.85 | KDR (0.60) | STING1KDRPDGFRBMAP2FLT3 | |
| SCHEMBL3879170 | 0.84 | MAP2 (0.72) | KDRPDGFRBMAP2KITFLT3 | |
| SCHEMBL3877605 | 0.84 | MAP2 (0.57) | STING1KDRPDGFRBMAP2KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7566736-B2 | Substituted indoles, compositions containing them, method for the production thereof and their use | AVENTIS PHARMA S.A. (FR) | 2009-07-28 | — | — | US | claimed |
| US-20070259910-A1 | Substituted Indoles, Compositions Containing Them, Method for the Production Thereof and Their Use | AVENTIS PHARMA S.A. (FR) | 2007-11-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259910-A1 | Substituted Indoles, Compositions Containing Them, Method for the Production Thereof and Their Use | IDO1, RB1, IDO2 | STING1 2749/4885KDR 1690/4885PDGFRB 1177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.