SCHEMBL3884640

SCHEMBL3884640

C[Si](C)(C)CNN

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31119423 0.61
SCHEMBL12927850 0.61
SCHEMBL6338590 0.61
SCHEMBL17017108 0.59
SCHEMBL7471058 0.57
SCHEMBL329326 0.57
SCHEMBL996456 0.56
SCHEMBL2210359 0.56
SCHEMBL11441374 0.56
SCHEMBL433960 0.56

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101426768-A Sulfonamide compounds useful as adg receptor modulators ASTRAZENECA AB (SE) 2009-05-06 CN disclosed
US-20090111860-A1 SULFONAMIDE COMPOUNDS USEFUL AS ADG RECEPTOR MODULATORS ASTRAZENECA AB (SE) 2009-04-30 US disclosed
EP-2013184-A1 SULFONAMIDE COMPOUNDS USEFUL AS EDG RECEPTOR MODULATORS AstraZeneca AB (SE) 2009-01-14 EP disclosed
WO-2007129019-A1 SULFONAMIDE COMPOUNDS USEFUL AS EDG RECEPTOR MODULATORS ASTRAZENECA AB (SE) 2007-11-15 WO disclosed
US-6013836-A PARTICULARLY ACTIVE AGAINST MOTHS AND BEETLES AND THEIR INSECT GROWTH REGULATING ACTIVITY WITHOUT ADVERSE IMPACT ON BENEFICIAL INSECTS; CROPS; FORESTRY ROHM AND HAAS COMPANY (US) 2000-01-11 US disclosed
US-5424333-A Anthelmintic N'-substituted-N,N'-disubstitutedhydrazines ROHM AND HAAS COMPANY (US) 1995-06-13 US disclosed
EP-0361645-B1 ORGANIC HYDRAZINE DERIVATIVES FOR PHARMACEUTICAL USE ROHM AND HAAS COMPANY (US) 1993-09-29 EP disclosed
US-5117057-A Insecticidal N' substituted-N-N'-disubstituted-hydrazines ROHM AND HAAS COMPANY (US) 1992-05-26 US disclosed
EP-0286746-B1 INSECTICIDAL N-(OPTIONALLY SUBSTITUTED) - N'-SUBSTITUTED-N,N'-DISUBSTITUTED- HYDRAZINES ROHM AND HAAS COMPANY (US) 1991-02-27 EP disclosed
EP-0361645-A2 Organic hydrazine derivatives for pharmaceutical use ROHM AND HAAS COMPANY (US) 1990-04-04 EP disclosed
CN-1039016-A N '-replacement-N, N '-two replaces the hydrazine insect repellent ROHM & HAAS (US) 1990-01-24 CN disclosed
EP-0286746-A1 Insecticidal N-(optionally substituted) - N'-substituted-N,N'-disubstituted- hydrazines ROHM AND HAAS COMPANY (US) 1988-10-19 EP disclosed