Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL284822 | 0.94 | TDP1 (0.34) | GABRR1LMNATDP1 | |
| Ammonia Solution, Strong SCHEMBL3115882 | 0.93 | TDP1 (0.38) | GABRR1LMNATDP1 | |
| Water SCHEMBL7794241 | 0.93 | TDP1 (0.33) | GABRR1LMNATDP1 | |
| Ammonia Solution, Strong SCHEMBL2157732 | 0.93 | TDP1 (0.38) | GABRR1LMNATDP1 | |
| Water SCHEMBL3638107 | 0.93 | TDP1 (0.33) | GABRR1LMNATDP1 | |
| Ammonia Solution, Strong SCHEMBL9615775 | 0.91 | TDP1 (0.37) | TDP1 | |
| SCHEMBL10324867 | 0.91 | TDP1 (0.32) | TDP1 | |
| SCHEMBL15253562 | 0.91 | TDP1 (0.32) | TDP1 | |
| Ammonia Solution, Strong SCHEMBL5718884 | 0.91 | TDP1 (0.37) | TDP1 | |
| Water SCHEMBL9324181 | 0.91 | TDP1 (0.32) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1922060-B1 | INTRAVENOUS PROPOFOL EMULSION COMPOSITIONS HAVING PRESERVATIVE EFFICACY | BHARAT SERUMS & VACCINES LTD (IN) | 2009-01-14 | — | — | EP | claimed |