Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 16/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.66 |
| ▸ | MEN1 | O00255 | 10/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 4/20 | 0.66 |
| ▸ | PKM | P14618 | 3/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | APP | P05067 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | INSR | P06213 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SNCA | P37840 | 6/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3887414 | 1.00 | MAPT (0.66) | MAPTKMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL3887417 | 1.00 | MAPT (0.66) | MAPTKMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL3891040 | 0.88 | MEN1 (0.55) | MAPTKMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL3891044 | 0.88 | MEN1 (0.55) | MAPTKMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL16081336 | 0.80 | MAPT (1.00) | MAPTKMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL15269395 | 0.79 | MEN1 (0.66) | MAPTKMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL15269391 | 0.79 | MEN1 (0.66) | MAPTKMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL15250730 | 0.79 | MEN1 (0.66) | MAPTKMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL28911495 | 0.77 | BCL2 (0.63) | MAPTKMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL3885808 | 0.73 | MAPT (0.58) | MAPTKMT2AMEN1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7534273-B2 | Cationic pyrazolone dyes, method for production thereof and coloring agents for keratin fibers containing said compounds | WELLA AG (DE) | 2009-05-19 | — | — | US | disclosed |
| US-20080263787-A1 | Cationic Pyrazolone Dyes, Method for Production Thereof and Coloring Agents for Keratin Fibers Containing Said Compounds | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2008-10-30 | — | — | US | disclosed |
| EP-1771517-A1 | CATIONIC PYRAZOLONE DYES METHOD FOR PRODUCTION THEREOF AND COLOURING AGENTS FOR KERATIN FIBRES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006012934-A1 | CATIONIC PYRAZOLONE DYES METHOD FOR PRODUCTION THEREOF AND COLOURING AGENTS FOR KERATIN FIBRES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080263787-A1 | Cationic Pyrazolone Dyes, Method for Production Thereof and Coloring Agents for Keratin Fibers Containing Said Compounds | KRT18, KLK5, IK | MAPT 1821/4885KMT2A 3682/4885MEN1 4265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.