Aniline

Aniline

SCHEMBL3890089

C[SiH](C)C.Nc1ccccc1

nearest known ligand 0.73

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.73
CYP3A4 P08684 5/20 0.50
TDP1 Q9NUW8 3/20 0.50
TAAR1 Q96RJ0 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MAPT P10636 6/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
KDM4E B2RXH2 2/20 0.44
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44
GFER P55789 1/20 0.44
MAOA P21397 6/20 0.43
MAOB P27338 6/20 0.43
ALDH1A1 P00352 2/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
HTT P42858 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL28306186 0.97 TSHR (0.69) TSHRCYP3A4TDP1TAAR1HSD17B10
Aniline SCHEMBL1984004 0.86
Aniline SCHEMBL11818606 0.86
SCHEMBL18517570 0.86 TSHR (1.00) TSHRCYP3A4TDP1TAAR1HSD17B10
Aniline SCHEMBL11803 0.86
Aniline SCHEMBL9755597 0.86 TSHR (1.00) TSHRCYP3A4TDP1TAAR1HSD17B10
Aniline SCHEMBL30876135 0.86
Aniline SCHEMBL16922171 0.86
SCHEMBL22096536 0.86 TSHR (1.00) TSHRCYP3A4TDP1TAAR1HSD17B10
Aniline SCHEMBL11811648 0.86 TSHR (1.00) TSHRCYP3A4TDP1TAAR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed