Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.71 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3904016 | 0.93 | DPP4 (0.79) | DPP4CHRM1GPR119 | |
| SCHEMBL3904026 | 0.93 | DPP4 (0.79) | DPP4CHRM1GPR119 | |
| SCHEMBL3892177 | 0.93 | DPP4 (0.69) | DPP4CHRM1GPR119 | |
| SCHEMBL3892157 | 0.92 | DPP4 (0.75) | DPP4CHRM1GPR119 | |
| SCHEMBL3904090 | 0.91 | DPP4 (0.69) | DPP4CHRM1GPR119 | |
| SCHEMBL3904102 | 0.91 | DPP4 (0.69) | DPP4CHRM1GPR119 | |
| SCHEMBL3889624 | 0.90 | DPP4 (0.68) | DPP4CHRM1GPR119 | |
| SCHEMBL3889582 | 0.90 | DPP4 (0.76) | DPP4CHRM1GPR119 | |
| SCHEMBL3895427 | 0.90 | DPP4 (0.70) | DPP4CHRM1GPR119 | |
| SCHEMBL3894198 | 0.90 | DPP4 (0.70) | DPP4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560450-B2 | Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM PHARMA GMBH & CO., KG (DE) | 2009-07-14 | — | — | US | disclosed |