Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.56 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA9 | Q16790 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.52 |
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GPX4 | P36969 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3901774 | 0.94 | NPC1 (0.57) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL4612127 | 0.93 | NPC1 (0.55) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL3925469 | 0.91 | NPC1 (0.57) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL4614995 | 0.91 | NPC1 (0.49) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL11430888 | 0.88 | NPC1 (0.49) | CA12CA1CA2CA9NPC1 | |
| Zinc Ion SCHEMBL137277 | 0.88 | NPC1 (0.49) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL3895225 | 0.81 | CA12 (0.48) | CA12CA1CA2CA9NPC1 | |
| SCHEMBL27655080 | 0.80 | NPC1 (0.62) | NPC1RAB9APAX8JAK2TACR1 | |
| SCHEMBL3893769 | 0.79 | CA12 (0.87) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL31514970 | 0.78 | NPC1 (0.64) | NPC1RAB9APAX8JAK2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1382592-B1 | Method for production of acrylic acid | NIPPON CATALYTIC CHEM IND (JP) | 2009-01-28 | — | — | EP | disclosed |