Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035023 | 0.86 | GLA (0.61) | MAPTALDH1A1TP53LMNAPOLB | |
| 4-Nitrophenyl Acetate SCHEMBL74985 | 0.86 | GAA (0.66) | MAPTALDH1A1TP53LMNASMN1; SMN2 | |
| SCHEMBL2313314 | 0.84 | MAPT (0.62) | MAPTALDH1A1TP53LMNASMN1; SMN2 | |
| 4-Nitrophenyl Acetate SCHEMBL11309102 | 0.84 | GAA (0.64) | MAPTALDH1A1LMNASMN1; SMN2POLB | |
| 4-Nitrophenyl Acetate SCHEMBL11309107 | 0.84 | GAA (0.64) | MAPTALDH1A1LMNASMN1; SMN2POLB | |
| 4-Nitrophenyl Acetate SCHEMBL21824458 | 0.84 | GAA (0.64) | MAPTALDH1A1LMNASMN1; SMN2POLB | |
| 4-Nitrophenyl Acetate SCHEMBL8769916 | 0.84 | GAA (0.64) | MAPTALDH1A1LMNASMN1; SMN2POLB | |
| 4-Nitrophenyl Acetate SCHEMBL3502992 | 0.84 | GAA (0.64) | MAPTALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL3044836 | 0.84 | MAPT (0.69) | MAPTALDH1A1TP53LMNASMN1; SMN2 | |
| 4-Nitrophenyl Acetate SCHEMBL8769946 | 0.82 | GAA (0.62) | MAPTALDH1A1TP53LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141837-A2 | PROCESS FOR PREPARING POSACONAZOLE AND INTERMEDIATES THEREOF | IND-SWIFT LABORATORIES LIMITED (IN) | 2009-11-26 | — | — | WO | disclosed |