Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3893529 | 1.00 | KCNH2 (0.60) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3548546 | 0.99 | KCNH2 (0.60) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3548543 | 0.99 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL13349122 | 0.89 | KCNH2 (0.66) | KCNH2 | |
| SCHEMBL3894661 | 0.87 | KCNH2 (0.66) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3543806 | 0.86 | KCNH2 (0.65) | KCNH2 | |
| SCHEMBL3547804 | 0.86 | KCNH2 (0.74) | KCNH2 | |
| SCHEMBL3545666 | 0.86 | KCNH2 (0.74) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3544556 | 0.85 | KCNH2 (0.73) | KCNH2 | |
| SCHEMBL3904304 | 0.85 | KCNH2 (0.66) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090137568-A1 | Tryclic Nitrogen Containing Compounds and their Use as Antibacterials | GLAXO GROUP LIMITED | 2009-05-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090137568-A1 | Tryclic Nitrogen Containing Compounds and their Use as Antibacterials | NRDC, NACA, ASNS | KCNH2 2161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.