Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.80 |
| ▸ | PPARD | Q03181 | 3/20 | 0.80 |
| ▸ | PPARA | Q07869 | 3/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 1/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.80 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.80 |
| ▸ | BLM | P54132 | 1/20 | 0.80 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.72 |
| ▸ | CYSLTR2 | Q9NS75 | 13/20 | 0.68 |
| ▸ | CYSLTR1 | Q9Y271 | 13/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6244980 | 0.98 | GRM2 (0.76) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL6937972 | 0.94 | PPARG (0.71) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL10952734 | 0.91 | CYSLTR2 (0.77) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL5128356 | 0.90 | PPARG (0.75) | PPARGPPARDPPARALMNACYP1A2 | |
| Methane SCHEMBL10959961 | 0.90 | CYSLTR2 (0.75) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL6444659 | 0.89 | PPARG (0.77) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL2067483 | 0.89 | PPARG (1.00) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL29369990 | 0.89 | PPARG (1.00) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL11023228 | 0.89 | PPARG (0.69) | PPARGPPARDPPARALMNACYP1A2 | |
| SCHEMBL11044280 | 0.87 | CYSLTR2 (0.78) | PPARGPPARDPPARALMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023907-B1 | MEDICINAL COMPOSITIONS WITH CHOLESTEROL-LOWERING EFFECT | ASTELLAS PHARMA INC (JP) | 2009-01-21 | — | — | EP | claimed |
| US-20080287544-A1 | Method for Screening Substance by Measuring PPAR DELTA Activating Effect and Agent | TEIJIN LIMITED (JP) | 2008-11-20 | — | — | US | claimed |
| US-20040265817-A1 | Method of selecting substance characterized by assaying ppard activating effect and drug | Outdoor Wireless Networks LLC | 2004-12-30 | — | — | US | claimed |
| EP-1416273-A1 | METHOD OF SELECTING SUBSTANCE CHARACTERIZED BY ASSAYING PPARD ACTIVATING EFFECT AND DRUG | TEIJIN LIMITED (JP) | 2004-05-06 | — | — | EP | claimed |
| EP-1023907-A1 | MEDICINAL COMPOSITIONS WITH CHOLESTEROL-LOWERING EFFECT | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2000-08-02 | — | — | EP | claimed |
| EP-1416273-B1 | METHOD OF SELECTING SUBSTANCE CHARACTERIZED BY ASSAYING PPARD ACTIVATING EFFECT AND DRUG | TEIJIN LTD (JP) | 2009-11-11 | — | — | EP | disclosed |
| EP-1023907-B1 | MEDICINAL COMPOSITIONS WITH CHOLESTEROL-LOWERING EFFECT | ASTELLAS PHARMA INC (JP) | 2009-01-21 | — | — | EP | disclosed |
| US-20080287544-A1 | Method for Screening Substance by Measuring PPAR DELTA Activating Effect and Agent | TEIJIN LIMITED (JP) | 2008-11-20 | — | — | US | disclosed |
| US-7396642-B2 | Methods of screening for a compound that enhances thermogenesis | TEIJIN LIMITED (JP) | 2008-07-08 | — | — | US | disclosed |
| US-20040265817-A1 | Method of selecting substance characterized by assaying ppard activating effect and drug | Outdoor Wireless Networks LLC | 2004-12-30 | — | — | US | disclosed |
| EP-1416273-A1 | METHOD OF SELECTING SUBSTANCE CHARACTERIZED BY ASSAYING PPARD ACTIVATING EFFECT AND DRUG | TEIJIN LIMITED (JP) | 2004-05-06 | — | — | EP | disclosed |
| US-6300364-B1 | FOR DECREASING LOW DENSITY LIPOPROTEIN CHOLESTEROL LEVEL | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-1023907-A1 | MEDICINAL COMPOSITIONS WITH CHOLESTEROL-LOWERING EFFECT | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2000-08-02 | — | — | EP | disclosed |