SCHEMBL3894508

SCHEMBL3894508

CC(O[SiH2]N)(c1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.44
ALDH1A1 P00352 2/20 0.41
TAAR1 Q96RJ0 1/20 0.41
ALOX15 P16050 1/20 0.41
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
KCNN4 O15554 5/20 0.39
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
CYP3A4 P08684 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
KIF11 P52732 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4171312 0.79 MAPK1 (0.46) MAPK1ALDH1A1TAAR1ALOX15MAPT
SCHEMBL23910519 0.77 MAPK1 (0.44) MAPK1ALDH1A1TAAR1ALOX15MAPT
SCHEMBL703381 0.76 MAPK1 (0.43) MAPK1ALDH1A1TAAR1ALOX15MAPT
SCHEMBL704841 0.76 MAPK1 (0.43) MAPK1ALDH1A1TAAR1ALOX15MAPT
SCHEMBL29167958 0.76 MAPK1 (0.43) MAPK1ALDH1A1TAAR1ALOX15MAPT
SCHEMBL15798273 0.76 MAPK1 (0.43) MAPK1ALDH1A1TAAR1ALOX15MAPT
SCHEMBL705911 0.76 MAPK1 (0.43) MAPK1ALDH1A1TAAR1ALOX15MAPT
SCHEMBL8639540 0.76 MAPK1 (0.43) MAPK1ALDH1A1TAAR1ALOX15MAPT
SCHEMBL8426498 0.73 MAPK1 (0.50) MAPK1ALDH1A1TAAR1ALOX15MAPT
SCHEMBL15953910 0.72 TAAR1 (0.52) MAPK1ALDH1A1TAAR1ALOX15CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7572303-B2 A symmetrical dialkyl carbonate, a metal, borong, silicon, or group 7 compound, a hydrogen or hydrocarbon-based fuel, an oxidizer, and a metallic cocatalyst; minimized hydrolysis; improved combustion and storage stability OCTANE INTERNATIONAL, LTD. (US) 2009-08-11 US disclosed
EP-0954558-B1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 2006-06-14 EP disclosed
US-20050044778-A1 Fuel compositions employing catalyst combustion structure OCTANE INTERNATIONAL, LTD. 2005-03-03 US disclosed
US-20040237384-A1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2004-12-02 US disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed
EP-1051461-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR, William C. (US) 2000-11-15 EP disclosed
WO-1999066009-A2 FUEL COMPOSITIONS EMPLOYING CATALYST COMBUSTION STRUCTURE ORR WILLIAM C (US) 1999-12-23 WO disclosed
EP-0954558-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR, William C. (US) 1999-11-10 EP disclosed
WO-1998026028-A1 FUEL COMPOSITIONS EXHIBITING IMPROVED FUEL STABILITY ORR WILLIAM C (US) 1998-06-18 WO disclosed