Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3895029

N=C(N)c1ccc(C(=O)NCCOc2cccc(C(=N)N)c2)cc1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
F10 P00742 8/20 0.86
PRSS1 P07477 9/20 0.63
PLG P00747 2/20 0.63
PROC P04070 1/20 0.63
KLK1 P06870 1/20 0.63
NPC1 O15118 1/20 0.56
HPGD P15428 1/20 0.56
RAB9A P51151 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
F2 P00734 2/20 0.54
PRSS2 P07478 1/20 0.54
C1S P09871 1/20 0.54
PRSS3 P35030 1/20 0.54
POLB P06746 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL3900211 0.97 F10 (0.80) F10PRSS1PLGPROCKLK1
Trifluoroacetic Acid SCHEMBL3903060 0.96 F10 (0.79) F10PRSS1PLGPROCKLK1
Trifluoroacetic Acid SCHEMBL3911547 0.95 F10 (0.77) F10PRSS1PLGPROCKLK1
Trifluoroacetic Acid SCHEMBL3911481 0.95 F10 (0.81) F10PRSS1PLGPROCKLK1
Trifluoroacetic Acid SCHEMBL3903054 0.95 F10 (0.77) F10PRSS1PLGPROCKLK1
Trifluoroacetic Acid SCHEMBL3912344 0.94 F10 (0.80) F10PRSS1PLGPROCKLK1
Trifluoroacetic Acid SCHEMBL3902464 0.94 F10 (0.76) F10PRSS1PLGPROCKLK1
Trifluoroacetic Acid SCHEMBL3907498 0.94 F10 (0.76) F10PRSS1PLGPROCKLK1
Trifluoroacetic Acid SCHEMBL3900623 0.94 F10 (0.79) F10PRSS1PLGPROCKLK1
Trifluoroacetic Acid SCHEMBL3895892 0.94 F10 (0.79) F10PRSS1PLGPROCKLK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0976722-B1 BENZAMIDINE DERIVATIVES AJINOMOTO KK (JP) 2009-03-11 EP disclosed
US-7396844-B1 Benzamidine derivatives AJINOMOTO CO., INC. (JP) 2008-07-08 US disclosed
EP-0976722-A1 BENZAMIDINE DERIVATIVES Ajinomoto Co., Inc. (JP) 2000-02-02 EP disclosed