Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTR3A | P46098 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525452 | 0.98 | KDM4E (0.54) | EPHX1GAASMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL25477818 | 0.96 | RAD52 (0.55) | EPHX1GAASMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL25477820 | 0.94 | RAD52 (0.53) | EPHX1GAASMN1; SMN2CYP1A2MAPK1 | |
| SCHEMBL4417188 | 0.89 | MAPT (0.53) | EPHX1GAASMN1; SMN2HTR3AKDM4E | |
| SCHEMBL25477811 | 0.88 | KDM4E (0.59) | HTR3AKDM4ERAD52CA12CA1 | |
| SCHEMBL25480324 | 0.88 | KDM4E (0.49) | EPHX1GAASMN1; SMN2HTR3AKDM4E | |
| SCHEMBL25480322 | 0.88 | RAD52 (0.49) | EPHX1GAAHTR3AKDM4EHSD17B10 | |
| SCHEMBL5488104 | 0.88 | KDM4E (0.57) | GAASMN1; SMN2CYP1A2MAPK1KDM4E | |
| SCHEMBL3893911 | 0.87 | CA12 (0.63) | CYP1A2KDM4ECA12CA1CA2 | |
| SCHEMBL17525453 | 0.86 | MAPT (0.51) | EPHX1GAASMN1; SMN2CYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023683-B2 | Catalyst compositions for improving polyurethane foam performance | EVONIK DEGUSSA GMBH (DE) | 2018-07-17 | — | — | US | claimed |
| US-9657129-B2 | Cyclic amine compound and process for producing polyurethane resin by using it | TOSOH CORPORATION (JP) | 2017-05-23 | — | — | US | claimed |
| EP-2657237-B1 | CYCLIC AMINE COMPOUND, AND PROCESS FOR PRODUCING POLYURETHANE RESIN USING SAME | TOSOH CORP (JP) | 2015-05-20 | — | — | EP | claimed |
| US-20130289232-A1 | NOVEL CYCLIC AMINE COMPOUND AND PROCESS FOR PRODUCING POLYURETHANE RESIN BY USING IT | TOSOH CORPORATION (JP) | 2013-10-31 | — | — | US | claimed |
| EP-2657237-A1 | NOVEL CYCLIC AMINE COMPOUND, AND PROCESS FOR PRODUCING POLYURETHANE RESIN USING SAME | Tosoh Corporation (JP) | 2013-10-30 | — | — | EP | claimed |
| EP-1867669-B1 | Catalyst compositions for improving polyurethane foam performance | AIR PROD & CHEM (US) | 2008-11-26 | — | — | EP | claimed |
| EP-1867669-A1 | Catalyst compositions for improving polyurethane foam performance | Air Products and Chemicals, Inc. (US) | 2007-12-19 | — | — | EP | claimed |
| US-20070287761-A1 | Catalyst compositions for improving polyurethane foam performance | EVONIK OPERATIONS GMBH (DE) | 2007-12-13 | — | — | US | claimed |
| EP-1443065-B1 | Low acid organometallic catalyst for the production of flexible, semi-flexible and rigid polyurethane foams | AIR PROD & CHEM (US) | 2006-09-13 | — | — | EP | claimed |
| EP-1534766-A1 | PROCESS FOR PREPARING POLYURETHANE FOAM | GENERAL ELECTRIC COMPANY (US) | 2005-06-01 | — | — | EP | claimed |
| US-6825238-B2 | BISMUTH CARBOXYLATE OR BISMUTH SULFONATE HAVING LESS THAN 34% FREE ACID AS THE ORGANOMETALLIC CATALYST | AIR PRODUCTS AND CHEMICALS, INC. | 2004-11-30 | — | — | US | claimed |
| US-6818675-B2 | USING REACTION PRODUCT OF TERTIARY AMINE AND ACID AS POLYMERIZATION CATALYST | GENERAL ELECTRIC COMPANY | 2004-11-16 | — | — | US | claimed |
| EP-0877042-B1 | Reactive catalyst compositions for improving water blown polyurethane foam performance | AIR PROD & CHEM (US) | 2004-09-22 | — | — | EP | claimed |
| EP-1443065-A1 | Low acid organometallic catalyst for the production of flexible, semi-flexible and rigid polyurethane foams | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2004-08-04 | — | — | EP | claimed |
| US-20040147626-A1 | LOW ACID ORGANOMETALLIC CATALYST FOR THE PRODUCTION OF FLEXIBLE, SEMI-FLEXIBLE AND RIGID POLYURETHANE FOAMS | EVONIK DEGUSSA GMBH (DE) | 2004-07-29 | — | — | US | claimed |
| WO-2004013201-A1 | PROCESS FOR PREPARING POLYURETHANE FOAM | GENERAL ELECTRIC COMPANY (US) | 2004-02-12 | — | — | WO | claimed |
| US-20040029986-A1 | Process for preparing polyurethane foam | CROMPTON CORPORATION | 2004-02-12 | — | — | US | claimed |
| US-6232356-B1 | INCREASING LOAD BEARING PROPERTIES OF POLYURETHANE FOAM USING UREA CATALYST | AIR PRODUCTS AND CHEMICALS, INC. | 2001-05-15 | — | — | US | claimed |
| US-6201033-B1 | IMPROVING COMPRESSIVE STRENGTH AND/OR AIRFLOW OF A FLEXIBLE POLYURETHANE FOAM BY REACTION OF A POLYISOCYANATE WITH A POLYOL AND WATER AS BLOWING AGENT CATALYZED BY A TERTIARY AMINE FREE OF UREA GROUPS AND A UREA COMPOUND | AIR PRODUCTS AND CHEMICAL, INC. | 2001-03-13 | — | — | US | claimed |
| EP-0877042-A1 | Reactive catalyst compositions for improving water blown polyurethane foam performance | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1998-11-11 | — | — | EP | claimed |