Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | KCNA3 | P22001 | 19/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900687 | 1.00 | MEN1 (0.78) | MEN1ALDH1A1KMT2AKCNA3 | |
| SCHEMBL3895509 | 1.00 | MEN1 (0.78) | MEN1ALDH1A1KMT2AKCNA3 | |
| SCHEMBL3896875 | 0.91 | MEN1 (0.78) | MEN1ALDH1A1KMT2AKCNA3 | |
| SCHEMBL3899256 | 0.90 | KCNA3 (0.78) | MEN1ALDH1A1KMT2AKCNA3 | |
| SCHEMBL3893644 | 0.90 | KCNA3 (0.82) | MEN1ALDH1A1KMT2AKCNA3 | |
| SCHEMBL3893648 | 0.90 | KCNA3 (0.82) | MEN1ALDH1A1KMT2AKCNA3 | |
| SCHEMBL3897148 | 0.90 | KCNA3 (0.78) | MEN1ALDH1A1KMT2AKCNA3 | |
| SCHEMBL3897141 | 0.90 | KCNA3 (0.78) | MEN1ALDH1A1KMT2AKCNA3 | |
| SCHEMBL3910722 | 0.89 | MEN1 (0.75) | MEN1ALDH1A1KMT2AKCNA3 | |
| SCHEMBL3895297 | 0.89 | KCNA3 (0.80) | MEN1ALDH1A1KMT2AKCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143965-B1 | CARBOCYCLIC POTASSIUM CHANNEL INHIBITORS | MERCK & CO INC (US) | 2009-02-25 | — | — | EP | disclosed |
| US-6632836-B1 | To treat autoimmune disorders, cardiac arrhythmias and the like | MERCK & CO., INC. | 2003-10-14 | — | — | US | disclosed |