⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897151 | 1.00 | — | — | |
| SCHEMBL3897157 | 1.00 | — | — | |
| SCHEMBL16347527 | 0.74 | — | — | |
| SCHEMBL16346066 | 0.74 | — | — | |
| SCHEMBL15291293 | 0.72 | EP300 (0.31) | — | |
| SCHEMBL14471644 | 0.72 | — | — | |
| SCHEMBL14471645 | 0.72 | — | — | |
| SCHEMBL14471641 | 0.72 | — | — | |
| SCHEMBL503841 | 0.72 | — | — | |
| SCHEMBL14394636 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375464-B1 | METHOD FOR ALDOL REACTION IN WATER | JAPAN SCIENCE & TECH AGENCY (JP) | 2009-03-04 | — | — | EP | disclosed |
| US-7323603-B2 | Reacting an aldehyde with a silyl enol ether in an aqueous medium in the presence of a boronic acid, a surfactant, and a Bronsted acid | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2008-01-29 | — | — | US | disclosed |
| US-7323603-B2 | Reacting an aldehyde with a silyl enol ether in an aqueous medium in the presence of a boronic acid, a surfactant, and a Bronsted acid | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2008-01-29 | — | — | US | disclosed |
| US-20040133044-A1 | Method for aldol reaction in water | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-07-08 | — | — | US | disclosed |
| EP-1375464-A1 | METHOD FOR ALDOL REACTION IN WATER | Japan Science and Technology Corporation (JP) | 2004-01-02 | — | — | EP | disclosed |
| EP-0614871-B1 | Process for producing optically active beta-hydroxyketone | TAKASAGO PERFUMERY CO LTD (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5434289-A | Process for producing optically active β-hydroxyketone | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-07-18 | — | — | US | disclosed |
| EP-0614871-A1 | Process for producing optically active beta-hydroxyketone | Takasago International Corporation (JP) | 1994-09-14 | — | — | EP | disclosed |