Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.75 |
| ▸ | F2 | P00734 | 4/20 | 0.75 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | PROC | P04070 | 1/20 | 0.37 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14132135 | 0.95 | F10 (0.83) | F10F2RAB9APRSS1NPC1 | |
| Trifluoroacetic Acid SCHEMBL3899621 | 0.93 | F10 (0.75) | F10F2RAB9AKMT2APRSS1 | |
| SCHEMBL14131792 | 0.88 | F10 (0.83) | F10F2RAB9APRSS1NPC1 | |
| SCHEMBL14132315 | 0.87 | F10 (1.00) | F10F2RAB9APRSS1NPC1 | |
| Trifluoroacetic Acid SCHEMBL3905673 | 0.83 | F10 (0.92) | F10F2PRSS1 | |
| Trifluoroacetic Acid SCHEMBL3905842 | 0.83 | F10 (0.72) | F10F2RAB9AKMT2APRSS1 | |
| Trifluoroacetic Acid SCHEMBL3902136 | 0.83 | F10 (0.74) | F10F2 | |
| Trifluoroacetic Acid SCHEMBL6865355 | 0.82 | F10 (0.64) | F10F2PRSS1PLGPROC | |
| Trifluoroacetic Acid SCHEMBL4684666 | 0.82 | F10 (0.67) | F10F2NPC1F3 | |
| SCHEMBL3899625 | 0.81 | F10 (0.62) | F10F2RAB9AKMT2APRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |