Trifluoroacetic Acid

SCHEMBL3898447

CN(C)C(=N)c1ccc(C(=O)N[C@@H](COc2cccc(C(=N)N)c2)CC(=O)O)cc1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.74

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	F10	P00742	12/20	0.74

▸	TMPRSS15	P98073	2/20	0.44

▸	F3	P13726	7/20	0.43

▸	F2	P00734	5/20	0.43

▸	F7	P08709	3/20	0.43

▸	PRSS1	P07477	1/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL13901150	0.95	F10 (0.83)	F10TMPRSS15F2PRSS1
Trifluoroacetic Acid SCHEMBL5105555	0.93	F10 (0.74)	F10TMPRSS15F3F2F7
Trifluoroacetic Acid SCHEMBL3897204	0.92	F10 (0.88)	F10TMPRSS15F3F2F7
Trifluoroacetic Acid SCHEMBL3902118	0.92	F10 (0.88)	F10TMPRSS15F3F2F7
Trifluoroacetic Acid SCHEMBL3902772	0.91	F10 (0.74)	F10TMPRSS15F3F2F7
Trifluoroacetic Acid SCHEMBL3900545	0.90	F10 (0.81)	F10TMPRSS15F3F2F7
Trifluoroacetic Acid SCHEMBL3901863	0.88	F10 (0.78)	F10TMPRSS15F3F2F7
Trifluoroacetic Acid SCHEMBL3900237	0.88	F10 (0.56)	F10TMPRSS15
Trifluoroacetic Acid SCHEMBL3900234	0.88	F10 (0.56)	F10TMPRSS15
SCHEMBL14131785	0.87	F10 (0.83)	F10F2PRSS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0976722-B1	BENZAMIDINE DERIVATIVES	AJINOMOTO KK (JP)	2009-03-11	—	—	EP	disclosed
US-7396844-B1	Benzamidine derivatives	AJINOMOTO CO., INC. (JP)	2008-07-08	—	—	US	disclosed