Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3898620

N=C(N)c1cccc(OCCN(Cc2ccccc2)C(=O)c2ccc(OC3CCN(C(=O)CN)CC3)cc2)c1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 15/20 0.52
MAPT P10636 1/20 0.45
F2 P00734 3/20 0.42
OPRK1 P41145 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14132034 0.96 F10 (0.56) F10MAPTF2OPRK1
Trifluoroacetic Acid SCHEMBL5099097 0.92 F10 (0.63) F10MAPTF2
Trifluoroacetic Acid SCHEMBL3901004 0.87 F10 (0.55) F10MAPTF2
SCHEMBL14132035 0.87 F10 (0.59) F10MAPTF2OPRK1
SCHEMBL3898204 0.87 F10 (0.66) F10MAPTF2
Trifluoroacetic Acid SCHEMBL3895645 0.83 F10 (0.67) F10F2
SCHEMBL14132205 0.82 F10 (0.60) F10MAPTF2
SCHEMBL14131822 0.78 F10 (0.74) F10F2
SCHEMBL13901068 0.77 F10 (0.57) F10F2
Trifluoroacetic Acid SCHEMBL3318113 0.77 F10 (0.60) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0976722-B1 BENZAMIDINE DERIVATIVES AJINOMOTO KK (JP) 2009-03-11 EP disclosed
US-7396844-B1 Benzamidine derivatives AJINOMOTO CO., INC. (JP) 2008-07-08 US disclosed
EP-0976722-A1 BENZAMIDINE DERIVATIVES Ajinomoto Co., Inc. (JP) 2000-02-02 EP disclosed