Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 3/20 | 0.58 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.48 |
| ▸ | RXRA | P19793 | 7/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.44 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900303 | 0.87 | NR1H2 (0.46) | SRD5A1RXRANR1H2NR1H3TRIM24 | |
| SCHEMBL3905080 | 0.87 | SRD5A1 (0.44) | SRD5A1EPHX2TRIM24GPR119GHSR | |
| SCHEMBL3913909 | 0.85 | SRD5A1 (0.43) | SRD5A1RXRANR1H2NR1H3EPHX2 | |
| SCHEMBL3907882 | 0.84 | TACR1 (0.48) | SRD5A1NOTUMTRIM24GPR119GHSR | |
| SCHEMBL3900759 | 0.83 | S1PR1 (0.48) | SRD5A1EPHX2TRIM24GPR119GHSR | |
| SCHEMBL13598255 | 0.83 | SRD5A1 (0.49) | SRD5A1NOTUMRXRANR1H2NR1H3 | |
| SCHEMBL3903504 | 0.83 | SRD5A1 (0.49) | SRD5A1NOTUMRXRANR1H2NR1H3 | |
| SCHEMBL3898860 | 0.83 | SRD5A1 (0.49) | SRD5A1NOTUMRXRANR1H2NR1H3 | |
| SCHEMBL3905018 | 0.83 | POLB (0.44) | SRD5A1NOTUMGPR119HTR2AHTR2C | |
| SCHEMBL3903499 | 0.82 | SRD5A1 (0.48) | SRD5A1NOTUMRXRANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | S1PR3, S1PR2, S1PR1 | SRD5A1 689/4885NOTUM 2224/4885RXRA 1301/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.