Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 8/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | C1S | P09871 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3896207 | 0.99 | F10 (0.48) | F10ITGB3ITGA2BPRSS1MEN1 | |
| SCHEMBL5105097 | 0.88 | F10 (0.62) | F10PRSS1 | |
| SCHEMBL3901372 | 0.87 | F10 (0.64) | F10PRSS1 | |
| SCHEMBL3903312 | 0.86 | PRSS1 (0.46) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL3903062 | 0.85 | F10 (0.52) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL3896379 | 0.84 | PRSS1 (0.50) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL3911553 | 0.84 | F10 (0.51) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL3912117 | 0.84 | PRSS1 (0.50) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL3901944 | 0.84 | PRSS1 (0.44) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL3897218 | 0.83 | F10 (0.49) | F10PRSS1F2PLGPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |