Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.65 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 3/20 | 0.39 |
| ▸ | F7 | P08709 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14132179 | 0.95 | F10 (0.72) | F10PRSS1F2ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL5105074 | 0.89 | F10 (0.62) | F10PRSS1F2ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL3902118 | 0.86 | F10 (0.88) | F10PRSS1F2ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL3897204 | 0.86 | F10 (0.88) | F10PRSS1F2ITGB3ITGA2B | |
| SCHEMBL14132294 | 0.85 | F10 (0.56) | F10PRSS1F2ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL3900545 | 0.84 | F10 (0.81) | F10PRSS1F2TMPRSS15F3 | |
| Trifluoroacetic Acid SCHEMBL3900529 | 0.84 | F10 (0.62) | F10PRSS1F2ITGB3ITGA2B | |
| SCHEMBL14131902 | 0.83 | F10 (0.68) | F10PRSS1F2ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL3901863 | 0.83 | F10 (0.78) | F10PRSS1F2TMPRSS15F3 | |
| Trifluoroacetic Acid SCHEMBL3901253 | 0.82 | F2 (0.49) | F10F2ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |