Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 15/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 10/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 10/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3912963 | 0.86 | S1PR1 (0.48) | LMNACYP3A4L3MBTL1S1PR1S1PR4 | |
| SCHEMBL13598591 | 0.82 | S1PR1 (0.48) | LMNACYP3A4L3MBTL1S1PR1S1PR4 | |
| SCHEMBL3901027 | 0.82 | S1PR1 (0.48) | S1PR1S1PR4S1PR5S1PR3CYP2C9 | |
| Hydrochloric Acid SCHEMBL3912875 | 0.81 | S1PR1 (0.48) | LMNACYP3A4L3MBTL1S1PR1S1PR4 | |
| SCHEMBL13598221 | 0.80 | S1PR1 (0.41) | LMNAS1PR1S1PR4S1PR5S1PR3 | |
| SCHEMBL3915392 | 0.80 | S1PR1 (0.50) | LMNACYP3A4L3MBTL1S1PR1S1PR4 | |
| SCHEMBL3909426 | 0.80 | DHODH (0.49) | S1PR1S1PR4S1PR5S1PR3TP53 | |
| Hydrochloric Acid SCHEMBL3915095 | 0.80 | S1PR1 (0.40) | LMNAS1PR1S1PR4S1PR5S1PR3 | |
| SCHEMBL3899114 | 0.79 | S1PR1 (0.46) | S1PR1S1PR4S1PR5S1PR3 | |
| Hydrochloric Acid SCHEMBL4416508 | 0.78 | S1PR1 (0.46) | LMNACYP3A4L3MBTL1S1PR1S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | S1PR3, S1PR2, S1PR1 | LMNA 3948/4885CYP3A4 1134/4885L3MBTL1 1651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.