Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 13/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 13/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 12/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.50 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3901354 | 0.86 | S1PR1 (0.51) | S1PR1S1PR5S1PR4S1PR3USP30 | |
| Hydrochloric Acid SCHEMBL3903871 | 0.86 | S1PR1 (0.51) | S1PR1S1PR5S1PR4S1PR3USP30 | |
| SCHEMBL3909549 | 0.86 | S1PR1 (0.51) | S1PR1S1PR5S1PR4S1PR3MAPT | |
| SCHEMBL3905173 | 0.85 | S1PR1 (0.43) | S1PR1S1PR5S1PR4S1PR3USP30 | |
| SCHEMBL3905177 | 0.85 | S1PR1 (0.43) | S1PR1S1PR5S1PR4S1PR3USP30 | |
| SCHEMBL3900600 | 0.85 | S1PR1 (0.48) | S1PR1S1PR5S1PR4S1PR3MAPT | |
| SCHEMBL3901780 | 0.84 | S1PR1 (0.42) | S1PR1S1PR5S1PR4S1PR3USP30 | |
| SCHEMBL13598225 | 0.83 | S1PR1 (0.48) | S1PR1S1PR5S1PR4S1PR3USP30 | |
| Hydrochloric Acid SCHEMBL3908179 | 0.82 | S1PR1 (0.47) | S1PR1S1PR5S1PR4S1PR3USP30 | |
| Hydrochloric Acid SCHEMBL3908183 | 0.82 | S1PR1 (0.47) | S1PR1S1PR5S1PR4S1PR3USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | S1PR3, S1PR2, S1PR1 | S1PR1 3/4885S1PR5 4/4885S1PR4 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.