Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.53 |
| ▸ | F2 | P00734 | 3/20 | 0.53 |
| ▸ | PLG | P00747 | 2/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | C1S | P09871 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | F3 | P13726 | 2/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | PROC | P04070 | 1/20 | 0.45 |
| ▸ | KLK1 | P06870 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14132049 | 0.94 | F10 (0.63) | F10PRSS1F2PLGPRSS2 | |
| Trifluoroacetic Acid SCHEMBL5096384 | 0.89 | F10 (0.54) | F10PRSS1F2PLGPRSS2 | |
| Trifluoroacetic Acid SCHEMBL3898068 | 0.87 | F10 (0.59) | F10PRSS1F2PLGPRSS2 | |
| Trifluoroacetic Acid SCHEMBL3896841 | 0.85 | F10 (0.54) | F10PRSS1F2PLGPRSS2 | |
| Trifluoroacetic Acid SCHEMBL3899583 | 0.85 | F10 (0.74) | F10PRSS1F2PLGPRSS2 | |
| Trifluoroacetic Acid SCHEMBL3900211 | 0.84 | F10 (0.80) | F10PRSS1F2PLGPRSS2 | |
| Trifluoroacetic Acid SCHEMBL3897942 | 0.83 | F10 (0.52) | F10PRSS1F2PLGPRSS2 | |
| Trifluoroacetic Acid SCHEMBL5092493 | 0.83 | F10 (0.52) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL14132281 | 0.82 | F10 (0.64) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL14132265 | 0.82 | F10 (0.57) | F10PRSS1F2PLGPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976722-B1 | BENZAMIDINE DERIVATIVES | AJINOMOTO KK (JP) | 2009-03-11 | — | — | EP | disclosed |
| US-7396844-B1 | Benzamidine derivatives | AJINOMOTO CO., INC. (JP) | 2008-07-08 | — | — | US | disclosed |
| EP-0976722-A1 | BENZAMIDINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2000-02-02 | — | — | EP | disclosed |