Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 18/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 15/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 13/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | C1S | P09871 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1029129 | 0.85 | PLK1 (0.52) | S1PR1PLK1S1PR5S1PR4S1PR3 | |
| SCHEMBL10112445 | 0.83 | PLK1 (0.51) | S1PR1PLK1S1PR5S1PR4S1PR3 | |
| SCHEMBL5988215 | 0.81 | PLK1 (0.49) | S1PR1PLK1S1PR5S1PR4S1PR3 | |
| SCHEMBL12956546 | 0.77 | S1PR1 (0.46) | S1PR1PLK1S1PR5S1PR4S1PR3 | |
| SCHEMBL2538238 | 0.75 | PLK1 (0.47) | S1PR1PLK1S1PR5S1PR4S1PR3 | |
| SCHEMBL8423071 | 0.74 | PLK1 (0.55) | S1PR1PLK1S1PR5S1PR4S1PR3 | |
| Ammonia Solution, Strong SCHEMBL4951074 | 0.73 | S1PR1 (0.58) | S1PR1PLK1S1PR5S1PR4S1PR3 | |
| SCHEMBL4949657 | 0.73 | S1PR1 (0.67) | S1PR1PLK1S1PR5S1PR4S1PR3 | |
| SCHEMBL3904435 | 0.72 | PLK1 (0.47) | S1PR1PLK1S1PR5S1PR4S1PR3 | |
| SCHEMBL4951077 | 0.72 | S1PR1 (0.62) | S1PR1S1PR5S1PR4S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | DAIICHI SANKYO COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
| EP-2017263-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2009-01-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324581-A1 | HETEROARYLAMIDE LOWER CARBOXYLIC ACID DERIVATIVE | S1PR3, S1PR2, S1PR1 | S1PR1 3/4885PLK1 671/4885S1PR5 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.