Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.42 |
| ▸ | GAPDH | P04406 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BMP1 | P13497 | 4/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5188811 | 0.94 | TSHR (0.55) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH | |
| SCHEMBL3900177 | 0.86 | TSHR (0.39) | TSHRSMN1; SMN2BMP1MMP12 | |
| SCHEMBL3901116 | 0.79 | CA1 (0.32) | — | |
| SCHEMBL3102134 | 0.77 | TSHR (0.68) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH | |
| SCHEMBL23851480 | 0.75 | TSHR (0.65) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH | |
| SCHEMBL17062948 | 0.75 | TSHR (0.65) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH | |
| SCHEMBL9396374 | 0.75 | TSHR (0.65) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH | |
| SCHEMBL9397942 | 0.75 | TSHR (0.65) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH | |
| SCHEMBL21694562 | 0.75 | TSHR (0.65) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH | |
| SCHEMBL9714695 | 0.75 | TSHR (0.65) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615629-B1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2009-03-18 | — | — | EP | claimed |
| EP-1615629-B1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2009-03-18 | — | — | EP | disclosed |
| EP-1615629-A4 | PEPTIDE DEFORMYLASE INHIBITORS | CHRISTENSEN SIEGFRIED B IV (US) | 2007-02-28 | — | — | EP | disclosed |
| EP-1615629-A1 | PEPTIDE DEFORMYLASE INHIBITORS | Christensen, Siegfried B. IV (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004098584-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-11-18 | — | — | WO | disclosed |